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  • 1995-1999  (3)
  • Key words Lithium  (2)
  • Alberta  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Cooking Oil: A Home Fire Hazard in Alberta, Canada (1997)
    Springer
    Fire technology 33 (1997), S. 140-166 
    Details
    ISSN: 1572-8099
    Keywords: Canada ; Alberta ; cooking equipment ; cooking oil ; fire injuries ; smoke point ; flash point ; fire hazard ; fire statistics ; prevention
    Source: Springer Online Journal Archives 1860-2000
    Topics: Architecture, Civil Engineering, Surveying
    Notes: Abstract This paper begins with a brief statistical analysis to establish the significant contribution of cooking equipment fires to fire losses and injuries in Canadian homes. Due to lack of comprehensive fire loss data for Canadian homes, further analysis is focused on Alberta data. The most frequent ignition scenario, based on a top-down analysis of Alberta home fires, was the ignition of overheated cooking oil in pots, deep-fat fryers, or pans heated on stove tops. These fires also accounted for the majority of home fire injuries. Fire characteristics of cooking oils, which point to the importance of maintaining oil temperatures below their flash points, and thermostatically controlled deep-fat fryers as the best available solution to the problem are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1015395001403
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Influence of body size on lithium levels in rats (1997)
    Springer
    Psychopharmacology 129 (1997), S. 23-26 
    Details
    ISSN: 1432-2072
    Keywords: Key words Lithium ; Dosage ; Body weight ; Route of administration ; Serum levels ; Sex ; Volume of distribution
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Lithium chloride was injected into rats by the intraperitoneal or intravenous route. The dose was proportional to body weight, in the conventional manner. Lithium levels in blood serum and organs were determined after 3–24 h. Within a given strain, large rats had higher levels than small rats. The size of the rats, and not their age, was the determining factor. The large rats had more adipose tissue than the small rats. Inasmuch as lithium distributes in body water, the excess fat in large rats reduces its volume of distribution, which may be responsible for raising the lithium levels in aqueous compartments, including serum. Male and female rats of equal body size developed equal lithium levels in serum.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002130050157
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Prevention of lithium nephrotoxicity in a novel one-hour model in rats (1998)
    Springer
    Psychopharmacology 138 (1998), S. 34-39 
    Details
    ISSN: 1432-2072
    Keywords: Key words Lithium ; Nephrotoxicity ; Rat
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract It is well established that lithium can cause morphologically visible damage to the kidneys of humans and animals. Although the clinical significance of its nephrotoxicity is debatable, it would be desirable to find a method to prevent lithium’s effect on the kidneys. Toward this end, we have developed a novel method for producing nephrotoxicity that will be useful for research on prevention. A single, large, toxic dose of lithium chloride (LiCl) caused necrosis of the distal convoluted tubules, which was visible by light microscopy in 30 min, had fully developed in 1 h, and had disappeared by the next day. The lesions were seen after IP or IV injections of fasted rats of three different strains. Equivalent doses of NaCl, KCl, MgCl2 and combinations thereof had no such effect, nor did they inhibit nephrotoxicity when incorporated into the LiCl solution. However, relatively small doses of LiCl injected by any route 3 or 24 h beforehand prevented the nephrotoxicity. The mechanism of prevention is not known, but it does not involve reduction of lithium levels in the kidneys.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002130050642
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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