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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Intensive care medicine 22 (1996), S. 409-414 
    ISSN: 1432-1238
    Keywords: Blood pressure ; Cardiac output ; Catherization ; Swan-Ganz ; Critical care ; Heart ; Monitoring physiologic ; Heart rate ; Thermodilution
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objective To determine whether changes in cardiac output are correlated with changes in other commonly measured covariables (heart rate, respiratory rate, mean arterial pressure, mean pulmonary artery pressure, pulmonary artery occlusion pressure, and temperature). Design Case series. Setting Medical intensive care unit (ICU) in a Veterans Administration Medical Center. Patients Twenty-three patients with Swan-Ganz catheters placed by the primary care team were studied on 25 occasions. Patients were managed by the primary team as clinically indicated. Interventions Thermodilution cardiac output and covariables were determined at baseline and at hourly intervals for the next 5 h. Each cardiac output measurement was calculated by averaging the last four of five individual measurements at each time point. Results The mean cardiac output (9.2l/min), heart rate (107/min), and pulmonary artery occlusion pressure (19 mmHg) were elevated. The hourly mean change in cardiac output was 10.2%. Using least-squares linear regression analysis, we found clinically significant changes in cardiac output (〉6.4%) to be most closely correlated with changes in heart rate (R 2=0.29,p〈0.001). Stepwise linear regression analysis showed that none of the other covariables added significantly to this relationship. No significant relationship was found between changes in cardiac output and changes in pulmonary artery occlusion pressure. Despite these correlations clinically significant changes in cardiac output were accompanied by changes in heart rate in the same direction only 62% of the time. Conclusion Changes in cardiac output were best correlated with changes in heart rate. Changes in pulmonary artery occlusion pressure were not correlated with changes in cardiac output in this population of medical ICU patients. A change in any of the covariables (alone or in combination) cannot be reliably used to indicate a simultaneous change in cardiac output.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Intensive care medicine 22 (1996), S. 409-414 
    ISSN: 1432-1238
    Keywords: Key words Blood pressure ; Cardiac output ; Catherization ; Swan-Ganz ; Critical care ; Heart ; Monitoring ; physiologic ; Heart rate ; Thermodilution
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Objective: To determine whether changes in cardiac output are correlated with changes in other commonly measured covariables (heart rate, respiratory rate, mean arterial pressure, mean pulmonary artery pressure, pulmonary artery occlusion pressure, and temperature). Design: Case series. Setting: Medical intensive care unit (ICU) in a Veterans Administration Medical Center. Patients: Twenty-three patients with Swan-Ganz catheters placed by the primary care team were studied on 25 occasions. Patients were managed by the primary team as clinically indicated. Interventions: Thermodilution cardiac output and covariables were determined at baseline and at hourly intervals for the next 5 h. Each cardiac output measurement was calculated by averaging the last four of five individual measurements at each time point. Results: The mean cardiac output (9.2 l/min), heart rate (107/min), and pulmonary artery occlusion pressure (19 mmHg) were elevated. The hourly mean change in cardiac output was 10.2%. Using least-squares linear regression analysis, we found clinically significant changes in cardiac output (〉6.4%) to be most closely correlated with changes in heart rate (R 2=0.29, p〈0.001). Stepwise linear regression analysis showed that none of the other covariables added significantly to this relationship. No significant relationship was found between changes in cardiac output and changes in pulmonary artery occlusion pressure. Despite these correlations clinically significant changes in cardiac output were accompanied by changes in heart rate in the same direction only 62% of the time. Conclusion: Changes in cardiac output were best correlated with changes in heart rate. Changes in pulmonary artery occlusion pressure were not correlated with changes in cardiac output in this population of medical ICU patients. A change in any of the covariables (alone or in combination) cannot be reliably used to indicate a simultaneous change in cardiac output.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 0021-9304
    Keywords: bonding-strength ; shear-strength ; simulated body fluid ; push-out measurement ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: This study was undertaken to evaluate the effect of coating characteristics on the mechanical strengths of the plasma-sprayed HA-coated Ti-6Al-4V implant system both in vitro and in vivo. Two types of HA coatings (HACs) with quite different microstructures, concentrations of impurity-phases, and indices-of-crystallinity were used. In vitro testings were done by measuring the bonding-strength at the Ti-6Al-4V-HAC interface, with HACs that had and had not been immersed in a pH-buffered, serum-added simulated body fluid (SBF). The shear-strength at the HAC-bone interface was investigated in a canine transcortical femoral model after 12 and 24 weeks of implantation. The results showed a bonding degradation of approximately 32% or higher of the original strength after 4 weeks of immersion in SBF, and this predominantly depended on the constructed microstructure of the HACs. After the push-out measurements, it was demonstrated that the HACs with higher bonding-strength in vitro would correspondingly result in significantly higher shear-strength at each implant period in vivo. Nevertheless, there were no substantial histological variations between the two types of HACs evaluated. The most important point elucidated in this study was that, among coating characteristics, the microstructure was the key factor in influencing the mechanical stability of the HACs both in vitro and in vivo. As a consequence, a denser HAC was needed to ensure mechanical stability at both interfaces. © 1997 John Wiley & Sons, Inc. J Biomed Mater Res, 37, 335-345, 1997.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    Surface and Interface Analysis 26 (1998), S. 984-994 
    ISSN: 0142-2421
    Keywords: ToF-SIMS ; SIMS ; metal ; contamination ; Si ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Physics
    Notes: Volumetric relative sensitivity factors (RSFs) are determined for 52Cr, 56Fe and 58Ni in an O2+-formed silicon oxide using a 12 keV Ga+ primary ion beam, and the influence of matrix oxygen content on these RSF values is evaluated. A multivariate expression for Si2+-referenced RSF values as a function of oxygen content is developed. This expression indicates that 12 keV Ga+ ion beam RSF values for 52Cr, 56Fe and 58Ni in O2+-formed oxide at 1.0 nm depth are in excellent agreement with well-established 8 keV O2+ RSF values in a silicon matrix. Because calculated RSF values for O2+-formed oxide at 1.0 nm depth and native silicon oxide are almost equivalent, time-of-flight (ToF) SIMS metal RSF values and detection limits in native oxide for a Ga+ liquid metal ion source are predicted, using the well-established 8 keV O2+ RSF values for metals in a silicon matrix. Time-of-flight SIMS silicon surface detection limits of 5×106 to 5×108 atoms cm-2 @ 0.5 nm are predicted for most metals of interest to the semiconductor community. © 1998 John Wiley & Sons, Ltd.
    Additional Material: 9 Ill.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    International Journal of Quantum Chemistry 62 (1997), S. 213-221 
    ISSN: 0020-7608
    Keywords: Chemistry ; Theoretical, Physical and Computational Chemistry
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Molecular orbital calculations of sixfold barriers in nitromethane, methyl boron difluoride, and trifluoronitromethane were performed by various Hartree-Fock and electron correlation methods. In those calculations, staggered and eclipsed conformations are of primary concern. These results indicated that for CH3NO2 and CH3BF2 the staggered conformations are more stable, while CF3NO2 has a more stable conformation in an eclipsed form. Both conformations do not differ significantly, which may account for the low internal rotational barrier of each molecule. Values of the barrier calculated by the Møller-Plesset perturbation and the quadratic configuration interaction methods did not match the experimental results. However, better internal rotational barrier values of each molecule were observed when the improved better basis sets and the Hartree-Fock method were selected. © 1997 John Wiley & Sons, Inc.
    Additional Material: 1 Ill.
    Type of Medium: Electronic Resource
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