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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Child's nervous system 14 (1998), S. 578-581 
    ISSN: 1433-0350
    Keywords: Key words Brain stem glioma ; Children ; Chemotherapy ; Prognosis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract We reviewed our experience with diffuse brain stem glioma (dBSG) to evaluate whether any improvement of outcome had occurred in our patients over the years. Of the 24 children referred to our department with suspected dBSG from 1981 to 1997, 5 had a different final diagnosis based on the clinical course. Mean survival in the remainder was 16±9.8 months from diagnosis. Survival increased with a longer interval from onset of symptoms to diagnosis (12.9±9.0 months with an interval of 1–4 weeks; 19.50±10.8 months with a longer interval). Visual symptoms at presentation were associated with a poorer prognosis. Survival was better in the 3- to 5-year age group (at diagnosis). Overall, a trend toward a slight improvement in survival was seen over the years, which we presumptively attribute to the introduction of intensive chemotherapy for these patients. We suggest that chemotherapy may be important in the management of dBSG until a better modality is found.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 35 (1997), S. 329-336 
    ISSN: 0021-9304
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: Detailed friction load-displacement response of four distinct metallic surfaces [one beaded porous metal (CTR) and three cast Co-Cr alloy ingrowth mesh surfaces, nonplanar mesh (INX), cast mesh 1 (CM1), and cash mesh 2 (CM2)] on polyurethane and cancellous bone specimens of six tibiae were measured under different normal stresses (0.1, 0.15, or 0.025 MPa). Bone cubes were obtained from different proximal regions of resurfaced cadaveric tibiae. Both monotonic and cyclic fatigue loadings of up to 4000 cycles at 1 Hz were considered. Comparison of measured results indicated that the friction coefficient was not affected by the magnitude of normal stress and the bone excision site (medial, lateral, anterior, posterior, and central). The CM2 surface showed significantly greater resistance with friction coefficients of more than 0.9 for the bone and 0.8 for the polyurethane. The INX surface yielded the second largest resistance followed by CMI and CTR surfaces. No significant difference was found between these latter two surfaces. Fatigue tests up to 4000 loading-unloading cycles showed about 10% reduction in friction coefficient for CTR and INX surfaces, while negligible reduction was found for CM1 and CM2 surfaces. © 1997 John Wiley & Sons, Inc.
    Additional Material: 8 Ill.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Hoboken, NJ : Wiley-Blackwell
    Journal of Biomedical Materials Research 41 (1998), S. 65-70 
    ISSN: 0021-9304
    Keywords: swelling ; conductivity ; hydrogels ; immobilized enzymes ; responsive polymers ; Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine , Technology
    Notes: The electrical characteristics of a glucose-sensitive polymeric hydrogel have been studied. The hydrogel matrices were prepared by radical polymerization of solutions containing 2-hydroxyethyl methacrylate, N,N-dimethyl aminoethyl methacrylate, tetraethylene glycol dimethacrylate, ethylene glycol, water, and glucose oxidase. The hydrogels displayed faster and higher swelling rates for lower levels of a crosslinking agent. Electrical conductivity was found to be a sensitive measurement of the state of the swelling. A simple model that relates hydrogel swelling and conductivity has been proposed. © 1998 John Wiley & Sons, Inc. J Biomed Mater Res, 41, 65-70, 1998.
    Additional Material: 7 Ill.
    Type of Medium: Electronic Resource
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