ISSN:
1435-232X
Keywords:
Key words DnaJ
;
MRJ
;
MSJ-1
;
J-domain
;
Chromosome 11q25
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
,
Medicine
Notes:
Abstract The DnaJ protein family consists of proteins with a highly conserved amino acid stretch called the "J - domain". A cDNA clone encoding a new protein with a J-domain was isolated from a human fetal brain cDNA library. This new member of the DnaJ family of 241 amino acid residues showed 94% identity with mouse Mrj (accession number, AF035962) and 71% identity with mouse Msj-1 (accession number, U95607) along its entire sequence. Reverse transcription - coupled polymerase chain reaction (RT-PCR) analysis showed the messenger RNA was ubiquitously expressed in various human tissues. The chromosomal location of the gene was determined by PCR-based analyses with both a human/rodent monochromosomal hybrid cell panel and a radiation hybrid panel to map on chromosome 11q25 region.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/s100380050139
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