Library

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • 1995-1999  (2)
  • Cost containment  (1)
  • In situ hybridization  (1)
  • 1
    ISSN: 1615-6102
    Keywords: Cellular evolution ; Epixenosomes ; Eukaryotes ; Prokaryotes ; Symbiosis ; In situ hybridization
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Epixenosomes live on the dorsal surface of their ciliate host,Euplotidium itoi. They lack a nuclear envelope and divide like prokaryotes. On the other hand they have a morphological and functional cell compartmentalization and possess tubules that are sensible to tubulin inhibitors and positively react with different antitubulin antibodies. In the present paper, as a first step to investigate their real nature, the in situ hybridization technique was applied at the ultrastructural level. Different prokaryotic and eukaryotic probes suitable for detecting rRNA genes were used. An additional test was performed with the gene encoding for β tubulin in the ciliateEuplotes crassus. Positive results, evidenced by a precise localization of gold particles, were obtained with all the eukaryotic probes used. These probes were obtained from organisms belonging to three different kingdoms (Protista, Animalia, Plantae). On the contrary, no hybridization was obtained with prokaryotic probes, not even when the probe used was an oligonucleotide complementary to all bacterial 16S rRNA so far sequenced. On the basis of these results and of the other observations so far accumulated, the possible eukaryotic nature of epixenosomes is discussed.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Neurological sciences 17 (1996), S. 99-103 
    ISSN: 1590-3478
    Keywords: Health care system reform ; Health care policies ; Managed care ; Disease management ; Cost containment ; Health care quality ; Biomedical innovation ; Biomedical research ; Neurological patient load ; Neurology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Sommario I tentativi di rinnovamento dei sistemi sanitari vigenti nei vari paesi sviluppati hanno lo scopo di contenere l'enorme crescita della spesa sanitaria. Le politiche rivolte al mero contenimento della spesa rischiano tuttavia di influenzare negativamente la qualità dell'assistenza. Per rinnovare i sistemi sanitari non basta porsi l'obiettivo di una maggiore efficienza dei servizi, ma occorre stabilire se le prestazioni erogate sono valide in termini di rapporto costi-efficacia e se le prestazioni stesse sono erogate in modo tempestivo e qualitativamente adeguato. Per realizzare l'obiettivo di migliorare la qualità dell'assistenza riducendo gli sprechi, è necessario investire sulla ricerca biomedica promuovendo studi di outcome in grado di fornire linee guida affidabili e valutare in modo adeguato i benefici connessi all'innovazione tecnologica, eliminando i fattori che favoriscono un uso distorto dell'innovazione stessa. Occorre altresì attivare forme organizzative che prevedano un maggior input dei medici e degli altri addetti all'assistenza nel processo decisionale ai vari livelli.
    Notes: Abstract The Author discusses some aspects of the Health Care systems in developed countries, and analyzes the reasons for the failure of recent reform programs to provide good quality service at a reasonable price. While not condemning business-style management completely, the Author points out how, in the neurological field too, under the control of physicians, biomedical research and innovation with inter-departmental collaboration can be managed according to specific aims, so as to prevent much costly and wasteful diagnostic and therapeutic practice, thus improving service quality while reducing hospital running costs.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...