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  • 1995-1999  (2)
  • Fluoxetine  (1)
  • Fractal analysis  (1)
  • Gepirone  (1)
  • 1
    ISSN: 1432-2072
    Keywords: Epilepsy ; Serotonin ; Fluoxetine ; Gepirone ; Long-term treatment ; Hippocampus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract This study assessed the effects of acute as well as long-term administration of fluoxetine, a selective serotonin (5-HT) reuptake inhibitor with anti-depressant properties, on hippocampal (HIP) seizures elicited by electrical stimulation in rats. The fluoxetine effect on HIP seizures was also assessed following long-term treatment with gepirone, a 5-HT1A receptor agonist. Acute single administration of fluoxetine (1, 10 mg/kg; IP) was found to produce no significant effect on HIP seizure activity. Following daily IP administration of fluoxetine (10 mg/kg per day) or gepirone (10 mg/kg per day) for 21 days, animals were given a 7-day drug-free period and then challenged with an acute dose of 10 mg/kg fluoxetine. These treatment regimens resulted in a significantly increased afterdischarge threshold of HIP seizures in response to acute fluoxetine administration. The inhibitory effect of fluoxetine, however, was not present 4 weeks after long-term treatment with either fluoxetine or gepirone. The present results indicate that long-term treatment with these compounds enhances the antiepileptic effect of subsequent fluoxetine administration on the generation of HIP seizures. This effect is possibly related to the well-demonstrated evidence that fluoxetine and gepirone, on long-term treatment, facilitate net 5-HT neurotransmission through desensitization of presynaptic 5-HT autoreceptors.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of wood science 45 (1999), S. 10-18 
    ISSN: 1611-4663
    Keywords: Multiresolutional contrast ; Fractal analysis ; Gloss of wood ; Texture analysis ; Digital image analysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The gloss of wood is a unique texture compared to that of other materials. To express it quantitatively, two digital-image analyses were performed. One method was multiresolutional contrast analysis, which was the new method developed in this study. The other method was fractal image analysis. Twenty-four specimens, including solid woods, wood-plastic composites (WPCs), printed grains, and granites, were prepared. Digital images of specimens were obtained in five sizes and in two illuminant directions (perpendicular and parallel to the grain). The multiresolutional contrast values of perpendicular illuminated images were calculated and compared among specimens. The result of this quantitative analysis was that the gloss of wood was characterized by bright spots in a relatively small area. Using fractal analysis, the fractal dimension of a digital image was used as an index of brightness changes, not for expressing the self-similarity. These indices showed results similar to those of the multiresolutional contrast analysis.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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