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  • 1995-1999  (2)
  • Frontal and temporal cortex  (1)
  • MRI  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of paleolimnology 19 (1998), S. 255-264 
    ISSN: 1573-0417
    Keywords: Lake Winnipeg ; magnetic resonance ; MRI ; SPRITE ; sediment
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Geosciences
    Notes: Abstract As part of the Geologic Survey of Canada (GSC) Lake Winnipeg Study, we have successfully imaged the Lake Agassiz to Lake Winnipeg transition in Section 4 of Core Namao 94-900-122a (i.e., from 313 cm to 465 cm), using a newly-developed magnetic resonance imaging (MRI) technique called SPRITE (Single-Point, Ramped Imaging with T1 Enhancement). Whole core, gamma-ray attenuation measurements have been used to calculate the bulk porosity of the sediment at 1 cm intervals for comparison with the SPRITE images. Image contrast and image intensities observed in the SPRITE images of Section 4 are related to local porosity and magnetic susceptibility variations. In general, regions of the core with low signal intensity contain high porosity and low magnetic susceptibility. The best contrast between sediment layers is observed from regions of the core with high magnetic susceptibility. High signal intensity is observed from regions with low porosity and/or high magnetic susceptibility.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1432-0533
    Keywords: Key words Pick’s disease ; Pick bodies ; Frontal and temporal cortex ; Alzheimer’s disease ; Principal ; components analysis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The densities of Pick bodies (PB), Pick cells (PC), senile plaques (SP) and neurofibrillary tangles (NFT) in the frontal and temporal lobe were determined in ten patients diagnosed with Pick’s disease (PD). The density of PB was significantly higher in the dentate gyrus granule cells compared with the cortex and the CA sectors of the hippocampus. Within the hippocampus, the highest densities of PB were observed in sector CA1. PC were absent in the dentate gyrus and no significant differences in PC density were observed in the remaining brain regions. With the exception of two patients, the densities of SP and NFT were low with no significant differences in mean densities between cortical regions. In the hippocampus, the density of NFT was greatest in sector CA1. PB and PC densities were positively correlated in the frontal cortex but no correlations were observed between the PD and AD lesions. A principal components analysis (PCA) of the neuropathological variables suggested that variations in the densities of SP in the frontal cortex, temporal cortex and hippocampus were the most important sources of heterogeneity within the patient group. Variations in the densities of PB and NFT in the temporal cortex and hippocampus were of secondary importance. In addition, the PCA suggested that two of the ten patients were atypical. One patient had a higher than average density of SP and one familial patient had a higher density of NFT but few SP.
    Type of Medium: Electronic Resource
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