Library

feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • 1995-1999  (2)
  • HIV-1  (1)
  • Transfer peptides  (1)
  • coupled conduction and radiation  (1)
  • 1
    ISSN: 1432-1440
    Keywords: Key words c-Myb antisense oligodeoxynucleotides ; Cell proliferation ; HIV-1 ; Integrin receptors ; Transfer peptides
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  Integrin receptor-targeted transfer of oligodeoxynucleotides (ODNs) by small synthetic peptides was used for improving delivery of antisense ODNs. An 18-mer phosphodiester bond containing ODN complementary to c-myb-encoded mRNA was complexed with several transfer peptides, containing as their parts two modules: (a) an RGD-motif as targeting sequence for integrin receptor and (b) nucleocapsid protein (NCp) 7 of HIV-1 or NCp7-derived peptides for complex formation with the ODNs. The amount of antisense ODN required for the inhibition of proliferation of human myeloid cell line HL-60 in vitro can be more than 50-fold reduced by complexing with transfer peptides. The efficiency of antisense delivery was increased by multimerization of the targeting sequence for the integrin receptor. Competition with integrin peptide abolished the effect, indicating that the integrin receptor is indeed responsible for the reaction.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
  • 2
    Electronic Resource
    Electronic Resource
    Springer
    International journal of thermophysics 19 (1998), S. 951-959 
    ISSN: 1572-9567
    Keywords: coupled conduction and radiation ; diamond films ; diffusivity ; laser-flash stimulation ; semifitransparent films ; transient technique
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract A laser-flash technique with fast infrared detection for the measurement of the normal diffusivity of samples, with a thickness in the range 200 to 700 μm, is presented. The experimental apparatus for such a measurement is described. Some points specific to the diffusivity measurement of semi-transparent and highly conductive materials such as diamond are discussed. Particularly, difficulties in connection with the good conductivity and low thickness of the samples we consider are pointed out. Finally, experimental results performed within the framework of the Diamond Round Robin 2 tests for both nondiamond and diamond films are presented and the influence of the coupled conductive–radiative heat transfer is shown.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...