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  • 1995-1999  (2)
  • Key words: Candida, funisitis, umbilical cord, placenta, fetus, infection  (1)
  • Key words: cocaine, placenta, pathology  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Effects of Cocaine on the Placenta (1999)
    Springer
    Pediatric and developmental pathology 2 (1999), S. 143-147 
    Details
    ISSN: 1615-5742
    Keywords: Key words: cocaine, placenta, pathology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: ABSTRACT Adverse perinatal outcomes of gravidas using cocaine is well documented, but the effects on the placenta have been difficult to elucidate due to confounding factors such as concurrent use of other drugs. This study compares pathologic findings of 26 placentas from women who used only cocaine during pregnancy with findings from 26 controls. All women were from a similar socioeconomic class and were controlled for gestational age and tobacco use. None of the cocaine placentas were from women whose toxicology screens were positive for drugs other than cocaine. In the 26 cocaine placentas, there was 1 infarct, 3 chronic villitis, and 1 segmental fibrosis, with none present in the controls. In the control group, there was 1 decidual vasculopathy and 1 thrombus in a maternal vessel, but none were in the cocaine placentas. Each group had 1 thrombus in a fetal vessel. The study group showed 6 cases of chorioamnionitis and 1 funisitis; the control group had 10 and 4 cases, respectively. None of the above or seven other features showed a statistically significant difference between the cases and controls. Cocaine is a potent vasoconstrictive agent that blocks re-uptake of norepinephrine at the adrenergic nerve terminals. Our study suggests that cocaine does not cause an increased incidence of any of the 15 clearly recognizable placental features examined.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s100249900102
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Candida Funisitis: A Clinicopathologic Study of 32 Cases (1998)
    Springer
    Pediatric and developmental pathology 1 (1998), S. 118-124 
    Details
    ISSN: 1615-5742
    Keywords: Key words: Candida, funisitis, umbilical cord, placenta, fetus, infection
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: ABSTRACT We report on 32 cases of Candida funisitis and describe the associated clinicopathologic features. The Candida funisitis was characterized grossly by small, circumscribed, yellow-white nodules on the umbilical cord surface and, microscopically, by subamnionic microabscesses in which fungal organisms were demonstrable. Chorioamnionitis was present in all cases. Twenty-four (75%) of the 32 infants were premature. There were 7 perinatal deaths, all in immature fetuses. Five (16%) of the 32 fetuses had congenital candidiasis. Five (16%) of the mothers had a history of intrauterine foreign body, including intrauterine contraceptive device in three and cervical cerclage in two. The diagnosis of Candida funisitis should prompt a careful examination for fetal infection, even though it is associated with congenital candidiasis in only a minority of the cases.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s100249900014
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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