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  • 1995-1999  (3)
  • Preterm  (2)
  • Key words Conjunctival cytology   (1)
  • 1
    ISSN: 1432-1076
    Keywords: Key words Conjunctival cytology  ;  Newborn Retinol status
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The preterm infant is deficient in vitamin A (retinol) and this has been implicated in the pathogenesis of chronic lung disease of prematurity. Conjunctival impression cytology (CIC) has been used in adults to assess retinol status. We aimed to assess the feasibility of performing CIC in the preterm infant and to determine the significance of abnormal CIC findings. CIC samples were collected during routine retinopathy screening, and classified as inadequate, normal, borderline normal or abnormal. Ninety preterm infants were studied. Seventy-four (82%) CIC specimens produced a positive yield, whereas 16 (18%) were inadequate. Of the 74 adequate samples, 61 (82%) were normal or borderline normal and 13 (18%) abnormal. Seventy-three CIC specimens were assessed by a second histopathologist with complete agreement on 64 (88%) samples and disagreement on 9 (12%) samples. Ten sets of conjunctival impressions, taken from both eyes, gave identical results in all adequate samples. Birth weight was significantly lower in this abnormal group. Four infants (32%) in the abnormal group required treatment for retinopathy compared to two (3%) in the normal/borderline normal group. (P 〈 0.01) Conclusion Conjunctival impression cytology is simple and reproducible technique which maybe easily applied to the preterm infant. Abnormal CIC is associated with retinopathy of prematurity requiring treatment.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 154 (1995), S. 222-224 
    ISSN: 1432-1076
    Keywords: Key words Oximetry ; Hyperoxaemia ; Preterm
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract When deciding an appropriate upper limit for pulse oxygen saturation (SpO2) in preterm infants the usefuleness of current data is limited by the fact that previous studies have examined a population of more mature infants and children or have applied various exclusion criteria which produce results unrepresentative of clinical practice. We tested the hypothesis of previous workers that maintaining the SpO2 below 98% would ensure an arterial oxygen tension (PaO2) less than 12 kPa. A total of 477 simultaneous measurements of PaO2 and SpO2 were made using Ohmeda Biox oximeters on 43 infants who were less than 33 weeks gestation and receiving supplementary oxygen. Of 435 measurements performed when the SpO2 was 97% or less, 26 (6%) had a PaO2 greater than 12 kPa. Further examination of the data showed that of 108 estimations performed when the SpO2 was less than 94%, none had a PaO2 greater than 12 kPa. Conclusion When using Ohmeda Biox pulse oximeters an upper limit of 97% for SaO2 is not effective in preventing hyperoxaemia; however, a limit of 93% is likely to maintain the PaO2 below 12 kPa.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    European journal of pediatrics 154 (1995), S. 222-224 
    ISSN: 1432-1076
    Keywords: Oximetry ; Hyperoxaemia ; Preterm
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract When deciding an appropriate upper limit for pulse oxygen saturation (SpO2) in preterm infants the usefuleness of current data is limited by the fact that previous studies have examined a population of more mature infants and children or have applied various exclusion criteria which produce results unrepresentative of clinical practice. We tested the hypothesis of previous workers that maintaining the SpO2 below 98% would ensure an arterial oxygen tension (PaO2) less than 12 kPa. A total of 477 simultaneous measurements ofPaO2 and SpO2 were made using Ohmeda Biox oximeters on 43 infants who were less than 33 weeks gestation and receiving supplementary oxygen. Of 435 measurements performed when the SpO2 was 97% or less, 26 (6%) had aPaO2 greater than 12 kPa. Further examination of the data showed that of 108 estimations performed when the SpO2 was less than 94%, none had aPaO2 greater than 12kPa. Conclusion When using Ohmeda Biox pulse oximeters an upper limit of 97% for SaO2 is not effective in preventing hyperoxaemia; however, a linit of 93% is likely to maintain thePaO2 below 12 kPa.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
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