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  • 1
    Electronic Resource
    Electronic Resource
    Relevance of birth month in respiratory allergy (1997)
    Oxford, UK : Blackwell Publishing Ltd
    Allergy 52 (1997), S. 0 
    Details
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1398-9995.1997.tb00984.x
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  • 2
    Electronic Resource
    Electronic Resource
    Isolation, characterization, and properties of a trypsin-chymotrypsin inhibitor from amaranth seeds (1996)
    Springer
    The protein journal 15 (1996), S. 219-229 
    Details
    ISSN: 1573-4943
    Keywords: Amaranthus hypochondriacus ; amaranth trypsin-chymotrypsin inhibitor ; protease inhibitors and MCF7 breast cancer cells
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract A trypsin-chymotrypsin inhibitor was isolated from the seeds of amaranth—a highly nutritious protein source. The purification of the inhibitor (AmI) was carried out by affinity chromatography on trypsin-Sepharose and by HPLC. AmI is a single-chain protein of 8 kD, as determined by electrophoresis on SDS-polyacrylamide gels and by gel exclusion on Sephadex G-50 column. It is stable at neutral and alkalinepH and is relatively thermostable. AmI inhibits trypsin and chymotrypsin from the digestive system of insects such asTribolium castaneum andLocusta migratoria, supporting the hypothesis that inhibitors may have evolved as defense mechanisms of seeds against insects. AmI lost its inhibitory activities when submitted to limited proteolysis with trypsin, while limited proteolysis with chymotrypsin had almost no effect. The partial amino acid sequence of 45 amino acids from the amino terminus of AmI differs significantly from the known sequences of legume-seed and cereal-grain protease inhibitor families. Differences in the chemistry at the inhibitory site(s) and in the amino acid sequence of AmI in comparison to that of other cereal and legume inhibitors suggest that AmI is a member of a new family of serine protease inhibitors. AmI was found to inhibit the anchorage-independent growth of MCF-7 breast cancer cells, suggesting that AmI may have anticarcinogenic activity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01887402
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  • 3
    Electronic Resource
    Electronic Resource
    The distribution pattern of Sarcocystis species, their transmission and pathogenesis in sheep in Fars Province of Iran (1996)
    Springer
    Veterinary research communications 20 (1996), S. 243-253 
    Details
    ISSN: 1573-7446
    Keywords: epidemiology ; infectivity ; nomads ; pathology ; prevalence ; Sarcocystis ; sheep
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Of 1362 sheep examined during two years in Fars Province of Iran, 786 (57.7%) were positive for Sarcocystis spp. The prevalence was significantly higher (p〈0.05) in animals owned by nomadic Assyrians (67.95%) than in those owned by local people (41.86%). More of the animals above 2 years age were infected (69.98%) than young ones (30.02%). Females had a higher prevalence of infection (61.07%) than males (38.93%) but most of the males were younger. There was no variation in the infection rate during spring, summer or autumn, but it was low in winter. The species observed were Sarcocystis gigantea, predominantly in oesophagus, S. medusiformis, mainly in diaphragm, S. tenella in the oesophagus, diaphragm, tongue and heart, and S. arieticanis in the oesophagus, tongue and occasionally in the diaphragm. In transmission studies, the prepatent period for S. gigantea and S. medusiformis and for the two microscopic species was 11–13, 10 and 8–12 days, respectively. The infection could not be transmitted to hamsters and guinea-pigs. The macroscopic species were almost non-pathogenic but were responsible for economic losses because of rejection of carcases or parts thereof at slaughter. The microscopic species caused tissue damage to the affected organs, resulting in haemorrhages, mononuclear infiltration and necrotic changes.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00366922
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  • 4
    Electronic Resource
    Electronic Resource
    Thermophilic actinomycetes in cane sugar mills: an aeromicrobiologic and seroepidemiologic study (1995)
    Springer
    Antonie van Leeuwenhoek 67 (1995), S. 339-344 
    Details
    ISSN: 1572-9699
    Keywords: thermophilic actinomycetes ; aerial prevalence ; bagassosis ; cane sugar mills ; T. sacchari ; precipitins
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract Aerial prevalence of clinically important thermophilic actinomycetes and occurrence of precipitating antibodies against them in sera of 153 exposed workers have been reported. The study was carried out in two cane sugar mills namely, the Upper Doab Sugar Mills and the Ramala Sugar Mills, located in north-west India. In both the sugar mills,T. sacchari was the predominant species, it accounted for 55.1% and 50.3% of the total population of thermophilic actinomycetes, followed byT. vulgaris (19.7% and 23.7%),T. thalpophilus (21.1% and 17.1%),Saccharomonospora viridis (3.4% and 5.0%) andSaccharopolyspora rectivirgula (Faenia rectivirgula) (0.7% and 3.9%), respectively. Precipitating antibodies against thermophilic actinomycetes were demonstrable in 34 (22.2%) workers;T. sacchari alone accounted for 20 of the positive precipitin reactions, followed byS. rectivirgula in 10. The mean absorbance values for IgG antibody activity againstT. sacchari as well asS. rectivirgula were found to be elevated significantly in the symptomatic workers than in the asymptomatic workers (p〈0.05) or unexposed controls (p〈0.001). However, the difference in IgG antibody activity was insignificant between precipitin-positive symptomatic workers and precipitin-positive asymptomatic workers. The results indicate that clinically important thermophilic actinomycetes are widely prevalent in cane sugar mills, andT. sacchari andS. rectivirgula are the major species involved in the sensitization of the bagasse workers in India.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00872932
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    Paper (German National Licenses)
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