ISSN:
0749-1581
Keywords:
NMR
;
1H NMR
;
13C NMR
;
6-s-trans-retinoids
;
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
A new class of vitamin A analogs (retinoids) was synthesized containing a dimethylene bridge to maintain a 6-s-trans conformation of the terminal double bonds. The 1H and 13C NMR spectra were assigned for 15 new compounds, including E-Z isomers (all-E, 13Z, 9Z and 9Z,13Z) of retinoids containing an ethyl ester and car-boxylic acid polar end groups, and also the (all-E)-isomer of the retinoids with an alcohol and aldehyde polar end-groups and five C15 intermediates. The assignments were based on long-range 1H—13C heteronuclear 2D experiments.
Additional Material:
1 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/mrc.1260330616
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