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  • 1
    ISSN: 1520-5827
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Oxford [u.a.] : International Union of Crystallography (IUCr)
    Acta crystallographica 52 (1996), S. 2385-2387 
    ISSN: 1600-5759
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    s.l. ; Stafa-Zurich, Switzerland
    Materials science forum Vol. 315-317 (July 1999), p. 228-235 
    ISSN: 1662-9752
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1349-9432
    Keywords: bacteriorhodopsin ; Z-scan ; nonlinear ; optics
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Nonlinear refractive index coefficient n2 of bacteriorhodopsin suspensions in water is measured by the Z-scan technique with a low power continuous wave laser at 647.1 manometer wavelength. Our results indicate that both the magnitude and the sign of n2 depend strongly on the light intensity. Negative values for n2 are obtained for on axis laser irradiance at the focus above 3 W/cm2. The observed self-defocusing phenomena can be attributed to the index change due to the light induced transition between the photochromic states. The results elucidate the origin of n2 and offer a plausible explanation for the differences in the reported n2 measurements.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1435-1803
    Keywords: Key words DX-9065a – factor X inhibitor – venous thrombosis – rabbit model – antithrombotic
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The objective of this study was to evaluate the effects of DX-9065a, a nonpeptide, direct inhibitor of factor Xa (FXa), in a novel experimental model of venous thrombosis. The experiments were conducted on anesthetized rabbits in which a veno-venous shunt with cotton threads was inserted into the vena cava. DX-9065a was administered intravenously to the rabbits as an initial bolus followed by a maintenance infusion using the following dosing schedules: ¶DX-I: 0.25 mg/kg+3 μ/kg/min.; DX-II: 0.75 mg/kg+9 μ/kg/min.; DX-III: 1.5 mg/kg+18 μ/kg/min.; DX-IV: 3.0 mg/kg+36 μ/kg/min.; DX-V: 6.0 mg/kg+72 μ/kg/min. DX-9065a induced a dose-dependent increase in the time to occlusion and a dose-dependent decrease in thrombus weight. Because of the unique character of the model, we were also able to show a dose-dependent increase in blood flow through the shunt. In addition, there were dose-dependent increases in prothrombin time (PT) and activated coagulation time (ACT) with more variable responses in the activated partial thromboplastin time (APTT). DX-9065a had little effect on thrombin time (TT) or bleeding time at all doses tested. In conclusion, dose-dependent antithrombotic efficacy was documented with DX-9065a in this new model of venous thrombosis. Although the in vivo potency of the compound was not striking, the results support the utility of FXa inhibition in venous thrombosis and demonstrate the utility of this experimental model for evaluating the efficacy of novel anti-coagulants.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1573-2711
    Keywords: lubricants ; additives ; Fourier transform infrared spectroscopy (FTIR) ; hard disks ; tribology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The retention characteristics of magnetic thin film media coated with perfluoropolyether (PFPE) lubricants and a phosphazene additive, X-1P, were investigated in this study. The retention performance was evaluated by a drag test with a waffle head sliding against the disk that was designed to mechanically wear out the lubricant layer. An IR beam was aligned on the test track to directly measure the amount of PFPE lubricants and X-1P left on the media surfaces for determining the retention characteristics of the lubricants. The drag test results show that under ambient and hot/wet conditions the media coated with AM3001 PFPE lubricant have higher retention ratio on the test track than those coated with ZDOL 2000 PFPE lubricant. The phosphazene additive X-1P was observed to strongly anchor on the surface and not easily removed as PFPE lubricants (ZDOL and AM3001). The retention characteristics of X-1P are independent of lube combination, either AM or ZDOL lubricants. It is demonstrated that X1-P exhibits a good antiwear property and excellent retention performance.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Tribology letters 5 (1998), S. 161-171 
    ISSN: 1573-2711
    Keywords: acoustic emission ; laser texture ; proximity contact recording
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract This work investigates the flying and contact phenomena of proximity contact recording sliders and their effects on the tribological performance of thin film media by the use of acoustic emission analysis. Proximity contact recording sliders included negative pressure and tri‐rail types of tripad sliders. Mechanical and laser‐induced textured magnetic rigid disks were used in this study. The laser bump heights of laser textured disks were controlled to achieve a desired tribological performance and the relationship between the laser bump heights and acoustic emission energy during drag and start/stop testing for different slider designs was studied. Emphasis was also placed on identifying the critical parameters of media and slider designs for tribological performance improvement. An analysis of the slider body natural frequencies during flying at the operational speed has been demonstrated to be well correlated to the contact behavior at the head‐disk interface. Moreover, the environmental and lubrication effects on the fixed tracking flyability performance were investigated and the acoustic emission data also agreed fairly well with the observed degree of contamination on sliders and degradation on the textured media.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Chichester [u.a.] : Wiley-Blackwell
    Surface and Interface Analysis 23 (1995), S. 416-425 
    ISSN: 0142-2421
    Keywords: Chemistry ; Polymer and Materials Science
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Physics
    Notes: Atomic force microscopy (AFM) is applied on two different types of thin latex films. Polystyrene dispersion particles are prepared by various methods to form well-ordered monolayers and multilayers. Atomic force microscopy serves as a tool to study the surface structures of such films and to find the optimal preparation conditions. The micromorphology of the second system, an adhesive tape, was imaged successfully by AFM running in dynamic mode. Besides the morphological studies, the interaction between the sticky surface and the AFM tip is measured by the damping of the cantilever oscillation versus tip-sample distance.
    Additional Material: 10 Ill.
    Type of Medium: Electronic Resource
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