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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of paleolimnology 19 (1998), S. 417-427 
    ISSN: 1573-0417
    Keywords: palynology ; Great Salt Lake ; climate ; Pliocene ; Pleistocene ; pluvial
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Geosciences
    Notes: Abstract Pollen analysis of 5 wells drilled to bedrock in the Great Salt Lake, Utah, USA provide a record vegetation change over the last ca 13.5 Ma. Over 440 pollen samples have been counted. The longest record presented is for the mid-lake Bridge Well. Close-interval (3–10 Ka) sampling is presented for the upper Indian Cove well. Chronologic control is provided by identification volcanic tephra and by K/Ar, Ar/Ar, and fission-track dates. Ash determinations are based on electron microprobe analyses of iron, calcium, and other elements compared to Neogene ash data at the University of Utah. Sedimentation begins 38 Ma, with good pollen preservation is sediments younger than 13.5 Ma, and no obvious gaps in sedimentation after 6 Ma. The upland vegetation is desert from the late Miocene onward, with Sarcobatus and Ephedra pollen dominance during the late Miocene (〈5 Ma). Chenopodiaceae-Amaranthus, and Artemisia gain dominance during the Pliocene (5–2.5 Ma) and early Pleistocene. Pinus and Artemisia sharply increase in the late Pleistocene (0.75 Ma). The pollen of 'Tertiary exotics' (elm, hickory, Ostrya-Carpinus) is rare, but persists into the Pleistocene. Major vegetation – climatic events occur 3.7 and 2.5 Ma. Increased pollen concentration and sedimentation rate after 310 Ka are attributed to the diversion of the Bear River into the Bonneville Basin. Glacial-interglacial cycles appear as alternations of Chenopodiaceae-Amaranthus (interglacial) vs Artemisia (glacial) during the Pliocene and early Pleistocene, and of Cupressaceae, Sarcobatus, and Gramineae (interglacial) vs Picea, Abies, and Pseudotsuga (glacial) during the late Pleistocene. Pluvial cycles are separated by interpluvial peaks in percentages of wetground and aquatic types. Six interpluvials are indicated during the last 759 Ka, with pluvial cycles of ca 100 Ka cyclicity back to 1.5 Ma.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of assisted reproduction and genetics 16 (1999), S. 509-511 
    ISSN: 1573-7330
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1573-7330
    Keywords: activin ; activin receptors ; semiquantitative RT-PCR ; gene expression ; embryo-endometrium interaction
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Purpose: Our purpose was to study the role of inhibin/activin during embryogenesis. Methods: Transcripts of inhibin/activin subunits (α, β A , β B ), activin receptors (types I and II), and follistatin were detected by a reverse transcriptase–polymerase chain reaction in human reproductive cells and preembryos cultured alone or co-cultured with human endometrial cells. Results: Transcripts of α, β A , β B subunits were all detected in granulosa luteal cells, but only β A units were detected in endometrial stromal and decidualized cells. In human preimplantation embryos, none of these subunits were detected in embryos from the four-cell to the morula stage and only β A subunits were detectable in blastocyst embryos. Activin receptors were detectable in all of the studied embryos and cells. Transcripts of β A , activin receptors, and follistatin were differentially expressed in human preimplantation embryos cultured in vitro and their expressions were significantly enhanced with the presence of endometrial stromal cells. Conclusions: Our data suggest that there is a possible endometrium–embryo interaction via endometrial activins and preimplantation embryo receptors and that the embryonic expressions of these activins, their receptors, and binding proteins are dependent on embryonic stage.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1573-7330
    Keywords: in vitro fertilization ; clomiphene citrate ; ovarian stimulation
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Purpose This study was carried out to evaluate the potential role of the combination clomiphene citrate/human menopausal gonadotropin (CC/hMG) for patients who failed previous in vitrofertilization (IVF) attempts with gonadotropin-releasing hormone analogs (GnRH- a) and/ or exogenous gonadotropins. Methods Patients were stimulated with CC/hMG (n=93) after unsuccessfully undergoing 182 gonadotropin cycles with (n=106) or without (n=76) luteal-phase GnRH- a. Cancellation rate, length of stimulation, and peak estradiol levels did not differ significantly between the two regimens. Results Although fewer oocytes were retrieved when the CC/hMG combination was used, 16 patients were able to successfully achieve a pregnancy (26.2% delivery rate/ transfer). When daily follicle stimulating hormone (FSH) levels were measured in two successive cycles in those women who conceived with the CC/hMG stimulation, baseline levels did not differ when compared with a previous GnRH-a/hMG cycle. Nevertheless, serum FSH levels rose rapidly and remained higher in the GnRH- a/hMG cycle, reaching significantly higher levels on day of human chorionic gonadotropin (hCG) administration. Conclusion Selected patients who failed previous IVF attempts with gonadotropins with or without GnRH analogs may benefit from the addition of CC to their ovarian stimulation protocol.
    Type of Medium: Electronic Resource
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