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  • 1
    Electronic Resource
    Electronic Resource
    Role of External and Internal Calcium on Heterocarrier-Mediated Transmitter Release (1996)
    Oxford, UK : Blackwell Science Ltd
    Journal of neurochemistry 66 (1996), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: Release-regulating heterocarriers exist on brain nerve endings. We have investigated in this study the mechanisms involved in the neurotransmitter release evoked by GABA heterocarrier activation. GABA increased the basal release of [3H]acetylcholine and [3H]noradrenaline from rat hippocampal synaptosomes and of [3H]dopamine from striatal synaptosomes. These GABA effects, insensitive to GABA receptor antagonists, were prevented by inhibiting GABA uptake but not by blocking noradrenaline, choline, or dopamine transport. Lack of extracellular Ca2+ or addition of tetrodotoxin selectively abolished the GABA-evoked release of [3H]noradrenaline, leaving unaffected that of [3H]acetylcholine or [3H]dopamine. 1,2-Bis(2-aminophenoxy)-ethane-N,N,N′,N′-tetraacetic acid acetoxymethyl ester (BAPTA-AM) or vesamicol attenuated the release of [3H]acetylcholine elicited by GABA. Reserpine, but not BAPTA-AM, prevented the effect of GABA on [3H]dopamine release. Autoreceptor activation inhibited the GABA-evoked release of [3H]noradrenaline but not that of [3H]acetylcholine or [3H]dopamine. It is concluded that (a) the release of [3H]noradrenaline consequent to activation of GABA heterocarriers sited on noradrenergic terminals meets the criteria of a conventional exocytotic process, (b) the extracellular [Ca2+]-independent releases of [3H]acetylcholine and [3H]dopamine appear to occur from vesicles possibly through involvement of intraterminal Ca2+, and (c) autoreceptor activation only affects heterocarrier-mediated vesicular release linked to entry of extracellular Ca2+.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1471-4159.1996.66041468.x
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Functionalization of Poly(organophosphazenes). VI. Substituent effect on the grafting reaction of maleic anhydride onto phenoxy-substituted phosphazene polymers (1996)
    Springer
    Journal of inorganic and organometallic polymers and materials 6 (1996), S. 367-383 
    Details
    ISSN: 1572-8870
    Keywords: Poly(organophosphazenes)(POPs) ; functionalization ; grafting reaction ; maleic anhydride ; phenoxy-substituted POPs
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract In this paper we describe the solution functionalization reaction of six phenoxysubstituted poly(organophosphazenes) with maleic anhydride and the effect of the phosphazene substituents on the overall grafting yield of anhydride moieties. It was found that the phosphazene polymer substituted with 4-ethylphenoxy groups is the most reactive of the whole series of exploited materials, while that bearing 4-t-butylphenoxy groups is the most inert one. This experimental reactivity trend observed in the grafting process is accounted for on the basis of both thermodynamic and steric factors.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01062515
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Shallow landslide hazard assessment using a physically based model and digital elevation data (1998)
    Springer
    Environmental geology 35 (1998), S. 81-88 
    Details
    ISSN: 1432-0495
    Keywords: Key words Shallow landslide ; Debris flow ; Subsurface flow ; Digital terrain model ; Dolomites
    Source: Springer Online Journal Archives 1860-2000
    Topics: Geosciences
    Notes: Abstract  A model for the analysis of topographic influence on shallow landslide initiation is applied to an experimental mountain basin where high-resolution digital elevation data are available: the Cordon catchment (5 km2) located in northern Italy. The model delineates those areas most prone to shallow landsliding due to surface topographic effects on hydrologic response. The model is composed of two parts: a steady-state model for shallow sub-surface runoff and an infinite-slope Coulomb failure model which assumes that the soil is cohesionless at failure. An inventory of landslide scars is used to document sites of instability and to provide a test of model performance by comparing observed landslide locations with model predictions. The model reproduces the observed distribution of landslide locations in a consistent way, although spatial variations in soil strength and transmissivity, which are not accounted for in the model, influence specific distribution of landslide areas within regions of similar topographic control.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/s002540050295
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
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