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  • 1995-1999  (4)
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  • 1
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 86 (1999), S. 6230-6233 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A Monte Carlo study of the electron transport in 2H-SiC is presented. The study is based on a three valley analytical band model that has been derived from an ab initio band structure calculation. The scattering models have been extrapolated from recent Monte Carlo simulations of 4H-SiC and 6H-SiC. The low field mobility in the c-axis direction is higher than in 4H-SiC and 6H-SiC, while the mobility perpendicular to the c axis is similar. The saturation velocity at 300 K obtained from the Monte Carlo simulation is 2.3×107 cm/s for field applied in the c-axis direction and 1.9×107 cm/s for field applied perpendicular to the c-axis direction. The difference in mean energy as a function of electric field between 2H-SiC and 4H-SiC or 6H-SiC is large. The energy spectrum along the c axis in 2H-SiC is not discontinuous as in the case of 4H-SiC and 6H-SiC, which gives 2H-SiC a higher mean energy for electric fields applied in the c-axis direction. This indicates that the electron impact ionization coefficients should be higher for 2H-SiC. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Fresenius' journal of analytical chemistry 354 (1996), S. 111-113 
    ISSN: 1432-1130
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract. A method using dual columns for measuring urinary albumin and creatinine is described, with fluorescence and UV detection, respectively. Short columns permit the use of a low pressure pumping system, and aqueous solvents are employed. With suitable combined UV-fluorescence optics, a simple, dedicated analyser is feasible.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1438-2199
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Collagen accumulation is a main pathological feature of diabetic cardiomyopathy. The underlying mechanisms seem to be increased cross linking by reactive carbonyles. The purpose of the study was to decrease the collagen content of total ventricular tissue by the oral administration of thiaproline, which could reduce collagen due to its functions as a proline analogue, blocking collagen production and as a free oxygen radical scavenger, blocking reactive carbonyles and oxygen species and subsequently collagen cross linking. Thiaproline was administered to genetically diabetic db/db mice and compared to untreated animals. Total ventricular collagen as expressed by hydroxyproline was significantly lower in the treated group (means 0.23 micromoles/10 tissue in the treated vs 0.35 micromoles/100 mg tissue in the untreated group, p 〈 0.001). Significantly more collagen could be eluted in the treated group (p 〈 0.001) and carboxymethyllysine was significantly reduced in the treated group (p 〈 0.001). Di-tyrosine and glycemic control did not differ between the groups. Glutathione was significantly increased in the TP treated experimental group (p 〈 0.001) and lipid peroxidation products were significantly decreased (means 0.221 absorbance in the treated group versus 0.321 absorbance in the untreated diabetic group) correlating with total ventricular collagen content (r = 0.87, p 〈 0.01). We conclude that thiaproline reduced total ventricular collagen content by inhibiting collagen cross linking as reflected by increased solubility of collagen and expressed by higher elution quantity of collagen. Thiaproline, and/or its metabolites induced increase of heart glutathione which may well have been scavenging reactive carbonyles derived from lipid peroxidation and advanced stage nonenzymatic glycosylation as shown by decreased total ventricular carboxy-methyllysine and lipid peroxidation products paralleling reduced heart collagen content. It remains to be shown that the successful reduction of heart collagen by thiaproline is paralleled by improved functional properties.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1573-2665
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
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