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  • 1
    ISSN: 0942-0940
    Keywords: Keywords: Endoscopic third ventriculostomy; occlusive hydrocephalus; pulsatility index; transcranial Doppler-sonography.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Objective . Endoscopic 3rd ventriculostomy has become the method of choice in the management of occlusive hydrocephalus. The treatment is accompanied by significantly less peri-operative complications than the cerebrospinal fluid shunting procedures previously employed. Close surveillance of patients, however, is necessary to avoid the consequences of raised intracranial pressure that may develop in case of obstruction of the artificial outlet of the 3rd ventricle.  The aim of this study was to confirm the value of transcranial Doppler-determined pulsatility index (pI) in the assessment of the patency of endoscopic 3rd ventriculostomy and to elucidate its usefulness in early postoperative recognition of increased intracranial pressure.  Methods. In twenty-two patients suffering from occlusive hydrocephalus, transcranial Doppler sonography (TCD) was performed before, immediately after, and five days after endoscopic fenestration of the floor of the 3rd ventricle. PI was defined with fast Fourier transformation. Mean PI values were determined in both middle cerebral arteries (MCA), over five cardiac cycles.  Results. In nineteen cases, PI values showed a significant decrease immediately as well as five days after the intervention as compared to the pre-operative values, and flow-sensitive MRI confirmed the patency of the fenestration in all cases. In one patient the operation failed to produce an effective diversion of cerebrospinal fluid as shown by flow-sensitive MRI, and the pulsatility index was unchanged. In two patients, a significant immediate postfenestration drop in PI was followed by a recurrence of PI to pre-operative levels without any clinical deterioration.  Conclusions. Preliminary results suggest that the transcranial Doppler-determined pulsatility index is a useful non-invasive tool for the evaluation of the patency of the fenestration in the early follow-up of patients who underwent endoscopic third ventriculostomy.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Applied physics 63 (1996), S. 481-484 
    ISSN: 1432-0649
    Keywords: 42.10 ; 42.60.E
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract The phase and the group velocities are calculated in a three-dimensional neighbourhood of the focus of an aberration-free lens illuminated by a spatially Gaussian beam. The Gouy phase shift caused by the diffraction results in superluminal pulse propagation on the optical axis within the Rayleigh range.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Springer
    Applied physics 63 (1996), S. 481-484 
    ISSN: 1432-0649
    Keywords: PACS: 42.10 ; 42.60.E
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract.  The phase and the group velocities are calculated in a three-dimensional neighbourhood of the focus of an aberration-free lens illuminated by a spatially Gaussian beam. The Gouy phase shift caused by the diffraction results in superluminal pulse propagation on the optical axis within the Rayleigh range.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Electrophoresis 17 (1996), S. 224-226 
    ISSN: 0173-0835
    Keywords: Preparative affinity electrophoresis ; Gradiflow ; Dextran blue ; Serum proteins ; Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Using the patented Gradiflow system in conjunction with newly developed affinity membranes, the suitability of an electrokinetic technique for affinity fractionation was investigated. Blue dextran incorporated into an affinity membrane was used to deplete a solution of horse serum of albumin, with the result that a majority of serum proteins were enriched tenfold relative to albumin. The technique, when fully developed, would offer some advantages over affinity chromatography, since to a degree it is possible to control which components of the sample are presented to the affinity matrix. Furthermore, the technique would extend the capabilities of the already multifunctional Gradiflow system.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Weinheim : Wiley-Blackwell
    Electrophoresis 16 (1995), S. 98-100 
    ISSN: 0173-0835
    Keywords: Preparative electrophoresis ; Membranes ; Serum albumin ; Reflux electrophoresis ; Chemistry ; Biochemistry and Biotechnology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: As part of the method for large-scale preparative electrophoresis across membranes of controlled porosity, we show that successive amounts of the leading component of a mixture migrating across a thin membrane can be collected by ‘reflux electrophoresis’. This consists of a series of cycles, in each of which the forward phase is stopped before the trailing components can emerge, the leading fraction is collected and the membrane cleared by reversing the current before commencing the next cycle. The reflux principle is demonstrated by separations based on size or on charge differences of protein molecules.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
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