ISSN:
0018-019X
Keywords:
Chemistry
;
Organic Chemistry
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
The synthesis of novel TbIII labels suitable for protein labelling are reported. Their luminescence properties as antibody conjugates were measured and compared to the results of corresponding TbIII chelates of the parent ligand structures. When the lowest triplet-state energy level of the parent donor ligand was over 23000 cm-1, i.e., the energy gap between the 5D4 level of TbIII and the lowest triplet-state energy level of the ligand exceeded 2600 cm-1, the label derivative with a long decay time (τ = 1.35-2.93 ms) and a high luminescence yield (ε. Φ = 3770-4560) was found to be suitable for bioaffinity assays.
Additional Material:
3 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/hlca.19970800204
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