ISSN:
1434-4475
Keywords:
Cyanamide
;
Imidoyl chlorides
;
Pyridinyl-4-pyrimidinamine
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Description / Table of Contents:
Zusammenfassung N-(1-Methyl-2-pyridin-3′(4′)-yl-vinyl)acetimidoyl-chloride (5, dargestellt durchBeckmann-Umlagerung der Oxime von 3-Methyl-4-pyridin-3′(4′)-yl-3-buten-2-onen (4)) reagieren mit Cyanamid und N,N-Dialkylcyanamid in Gegenwart von Titan(IV)chlorid zu 4-Amino-2,6-dimethyl-5-pyridinyl-pyrimidin-Derivaten (7).
Notes:
Summary N-(1-Methyl-2-pyridin-3′(4′)-yl-vinyl)acetimidoylchlorides (5, prepared byBeckmann rearrangement of the oximes of 3-methyl-4-pyridin-3′(4′)-yl-3-buten-2-ones (4)) react with cyanamide and N,N-dialkylcyanamides in the presence of titanium(IV) chloride to give 4-amino-2,6-dimethyl-5-pyridinyl-pyrimidine derivatives (7).
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00844691
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