ZIB

Hits per page

hits 1 - 2 | 2 hits

Sorting

Electronic Resource

Optic gliomas in children with neurofibromatosis type 1 (1991)

Lund, A. M. ; Skovby, F.

Springer

European journal of pediatrics 150 (1991), S. 835-838

add to mindlist on the mindlist

Details

ISSN: 1432-1076

Keywords: Neurofibromatosis type 1 ; Optic glioma ; Natural history ; Visual evoked potential

Source: Springer Online Journal Archives 1860-2000

Topics: Medicine

Notes: Abstract Over a 24-year period, optic gliomas were found in 29 children, 16 of whom had neurofibromatosis type 1 (NF-1). These 16 children comprised 21% of all children referred for management of NF-1 and its complications. The finding of optic glioma led to the diagnosis of NF-1 in 4 children. The mean age at diagnosis of optic glioma in NF-1 children was 6.4 years, and the average estimated duration of visual symptoms prior to diagnosis was 2.1 years. Most optic gliomas in NF-1 children were ascertained because of a visual complaint (69%), and an even greater number of children (88%) had an abnormal ophthalmological examination. The optic chiasm was involved in 75% of the patients. All of the seven children with optic glioma examined by visual evoked potential had an abnormal response ipsilateral to the tumour. The majority of the children received radiation therapy. After a mean follow up period of 5.8 years no deaths had occurred due to optic glioma, but in 35% of the children vision was worse. We conclude that optic glioma is a common, serious complication in NF-1 children. Routine care of such patients should include regular noninvasive investigations aimed at detecting lesions of the optic pathway.

Type of Medium: Electronic Resource

URL: http://dx.doi.org/10.1007/BF01955002

Permalink

Library	Location	Call Number	Volume/Issue/Year	Availability

Others were also interested in ...

Paper (German National Licenses)

Fulltext

Electronic Resource

Cationic and polymeric radicals of vinyl monomers in halogenated matrices: An ESR and SCF MO study (1988)

Tabata, M. ; Lund, A. ; Samskog, P. O. ; [et al.]

Bognor Regis [u.a.] : Wiley-Blackwell

Journal of Polymer Science Part A: Polymer Chemistry 26 (1988), S. 2725-2736

add to mindlist on the mindlist

Details

ISSN: 0887-624X

Keywords: Chemistry ; Polymer and Materials Science

Source: Wiley InterScience Backfile Collection 1832-2000

Topics: Chemistry and Pharmacology

Notes: The vinyl monomers methyl acrylate, methyl methacrylate, acrylic acid, methacrylic acid, and β-methylstyrene were dissolved in CF3CCl3, x-irradiated at 4 or 77 K, and investigated by ESR spectroscopy. The molecular cation of methyl acrylate has no resolved hyperfine structure, indicating that the unpaired electron is localized on the carbonyl oxygen. Evidence that a two-stage photoinduced reaction gives rise to a propagating radical was obtained. Propagating radicals were observed also with methyl methacrylate, acrylic acid, and methacrylic acid as solutes. The positive ion of β-methylstyrene has been prepared and characterized. The experimental data have been compared with molecular orbital calculations at different levels of approximation.

Additional Material: 6 Ill.