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  • 1
    Electronic Resource
    Electronic Resource
    Amorphization of Nd15Fe77B8 alloy ingots by mechanical grinding (1992)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 72 (1992), S. 5443-5447 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Amorphous powders of a Nd15Fe77B8 alloy were obtained by mechanical grinding of the alloy ingots. Mechanical grinding of Nd15Fe7B8 alloy ingots reduced the average particle size to 1 μm within the relatively short period of milling times. Extended milling did not yield further reduction in particle size, but resulted in a change in the structures from Nd2Fe14B crystallites to an amorphous structure. It was found that the crystallization of α-iron from amorphous matrix took place in some stage of milling. The amorphous materials were stable up to 820 K at a heating rate of 0.33 K/s. Heat treatment of the amorphous materials above the crystallization temperature resulted in the crystallization of the Nd2Fe14B phase and the resultant materials showed a high coercivity of 11.9 kOe as in the case for the amorphous Nd-Fe-B materials produced by rapid quenching techniques.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.351986
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  • 2
    Electronic Resource
    Electronic Resource
    Infertility treatment: from cookery to science. The epidemiology of randomised controlled trials (1993)
    Oxford, UK : Blackwell Publishing Ltd
    BJOG 100 (1993), S. 0 
    Details
    ISSN: 1471-0528
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Objectives To review the epidemiology of published randomised controlled trials in infertility treatment over the last 25 years, with special emphasis on the number and quality of trials.Design Computer literature review by MEDLINE backed up by a manual search of 41 journals. Each trial was classified according to the methodology described and quality criteria. The results were recorded in a computer database. Odds ratios (OR) and confidence intervals (CI) were calculated where the data were sufficient.Subjects Couples suffering from primary or secondary infertility. The trials studied 33 761 patients overall.Setting Institute of Epidemiology and Health Services Research, Leeds.Results Five hundred and one randomised trials in male and female infertility treatment were identified between 1966 and 1990. Pregnancy was an outcome in 291 (58%) and these were the subject of detailed analysis. Two hundred and twenty-four (77%) and 67 (23%) ‘pregnancy trials’ were concerned, respectively, with female and male infertility. Four per cent of the trials were preceded by a sample size calculation, and the average sample size was 96 patients (range 5–933); 700 patients per group would be required to demonstrate plausible success rates for most treatments. The method of randomisation was unstated or pseudo-randomised in 206 (71%) of trials where pregnancy was an outcome. Only 29 (5.8%) of studies were multicentre. The method of confirmation of pregnancy was omitted for 70% of papers. Cross-over design was used in 103 (21%) of cases. Meta-analysis is possible for selected topics such as the use of anti-oestrogens in idiopathic oligospermia and unexplained female infertility. Eight cases of double reporting were identified.Conclusions Trials using randomised methodology were relatively few in comparison with other branches of medicine, although their use is important in the evaluation of treatment for infertility as treatment-independent pregnancy is common. It was encouraging to note that an exponential increase in the use of this methodology occurred during the last three years, especially in association with assisted conception techniques, and meta-analysis has become possible for selected topics. However, many trials suffer from an unrealistically small sample size, inappropriate use of cross-over design or pseudo-randomisation. The trend towards properly controlled studies should be encouraged but these studies should be of improved quality and organised on a multicentre or even international basis.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1471-0528.1993.tb15142.x
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  • 3
    Electronic Resource
    Electronic Resource
    Novel method to fabricate corrugation for a λ/4-shifted distributed feedback laser using a grating photomask (1989)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 55 (1989), S. 415-417 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A novel method was developed to fabricate corrugation for a λ/4-shifted distributed feedback (DFB) laser. Mechanically ruled grating patterns were transferred photolithographically to the surface of an InP substrate. The resultant λ/4-shifted DFB laser operated in a single longitudinal mode at the Bragg wavelength.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.101882
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  • 4
    Electronic Resource
    Electronic Resource
    Angiosarcoma with dermal melanocytosis (1989)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of cutaneous pathology 16 (1989), S. 0 
    Details
    ISSN: 1600-0560
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: We report a case of angiosarcoma and dermal melanocytosis occurring simultaneously in the same lesion. We examined the primary and 2 metastatic lesions. Histopathologically, the anaplastic angiosarcoma cells had a tendency to form irregularly shaped small cavities. Immunohistochemically, they were strongly reactive with Ulex europaeus agglutinin (UEAI) stain. The mid and deep dermis of the same lesion had spindle or elongated slender melanocytes containing melanin granules. The melanocytes were positive with S-100 protein stain. Ultrastructurally, pinocytotic vesicles, fine filaments, and Weibel-Palade body-like dense granules were observed in the cytoplasm of angiosarcoma cells. Dermal melanocytes had external lamina and melanosomes in various stages. The melanocytes showed no similarity to the neoplastic tumor cells and there was no apparent intermediate form between the 2 kinds of cells. The etiological implications of dermal melanocytosis with a tumor of vascular origin are discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1600-0560.1989.tb00030.x
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  • 5
    Electronic Resource
    Electronic Resource
    Influence of Temperature and Time on Cooking Kinetics of Potatoes (1985)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 50 (1985), S. 0 
    Details
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: To study cooking kinetics, slices (6 mm thick, 30 mm diameter) of 3 potato varieties were treated in water at 90°, 100° and 110°C for varying times. Sensory, chemical and physical properties were investigated. Changes during cooking at constant temperature were mathematically described by a 0 order (texture, taste) and a 1st order (shear force, dry matter, pectin, soluble amylose, cell size) equation. The starch content remained constant. Temperature dependence of the rate constant could always be described by a first order equation. The z-values, which are necessary to calculate Cvalue for practical heat treatments, could be determined. Correlations established between kinetics of different properties showed that behavior of certain potato properties may be predicted by shear-force measurement.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2621.1985.tb13427.x
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  • 6
    Electronic Resource
    Electronic Resource
    Influence of the Composition of Potatoes on Their Cooking Kinetics (1985)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of food science 50 (1985), S. 0 
    Details
    ISSN: 1750-3841
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Agriculture, Forestry, Horticulture, Fishery, Domestic Science, Nutrition , Process Engineering, Biotechnology, Nutrition Technology
    Notes: A previous study of three potato varieties indicated that shear force measurement may be used to predict the behavior of certain potato properties during cooking. To verify this hypothesis and to confirm other previous findings, slices (6 mm thick, 30 mm in diameter) of 21 potato varieties were thermally treated in water at 100°C. Mathematical expressions were assessed, and coefficients were determined to describe the kinetic behavior of the varieties.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2621.1985.tb13428.x
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  • 7
    Electronic Resource
    Electronic Resource
    CHOLINERGIC NEUROMODULATION BY ATP, ADENOSINE AND ITS N6-SUBSTITUTED ANALOGUES IN GUINEA-PIG ILEUM (1985)
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental pharmacology and physiology 12 (1985), S. 0 
    Details
    ISSN: 1440-1681
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: 1. The effects of ATP, adenosine and N6-substituted adenosines, adenosine receptor agonists, on the twitch contraction of guinea-pig ileum evoked by transmural stimulation were evaluated.2. Adenosine and ATP produced an immediate and concentration dependent inhibition of the twitch, IC50 being 1.1 × 10−5 mol/l and 1.2 × 10−5 mol/l, respectively.3. N6-l-phenylisopropyl adenosine (L-PIA), N6-cyclohexyl adenosine (CHA) and N6-allyl adenosine also induced inhibitions which were gradual and persistent, IC50 being 2.6 × 10−8, 2.7 × 10−8 and 5.4 × 10−7 mol/l, respectively.4. Dipyridamole (10−7 mol/l), an adenosine uptake inhibitor, markedly augmented the inhibition evoked by adenosine and ATP, but not that by three N6-substituted adenosines, while theophylline (10−4mol/l) almost completely antagonized the inhibitory effects of all purine compounds. IC50 value of adenosine in the presence of dipyridamole (5 × 10−7 mol/l) was shifted to the left about 50 times from the control, whereas that of L-PIA was virtually unchanged.5. Tissue-medium ratios indicating uptake of [H]adenosine, [3H]ATP and [3H]CHA into the segment were 3.23 (s.e.m. =0.59), 3.59 (s.e.m. =0.78) and 0.41 (s.e.m. =0.04), respectively.6. These results suggest that not only adenosine and ATP but also these N6-substituted adenosines are potent agonists for the PI receptor, implying a similarity between PI and A, receptor in a functional role and these purine compounds may thereby modulate cholinergic neurotransmission by altering adenylate cyclase activity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1440-1681.1985.tb00305.x
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  • 8
    Electronic Resource
    Electronic Resource
    Lymphoblastic lymphoma in medaka, Oryzias latipes (Temminck et Schlegel) (1990)
    Oxford, UK : Blackwell Publishing Ltd
    Journal of fish diseases 13 (1990), S. 0 
    Details
    ISSN: 1365-2761
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Biology , Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1365-2761.1990.tb00771.x
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  • 9
    Electronic Resource
    Electronic Resource
    Two critical day lengths for the determination of wing forms and the induction of adult diapause in the water strider,Aquarius paludum (1993)
    Springer
    Naturwissenschaften 80 (1993), S. 430-432 
    Details
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01168342
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  • 10
    Electronic Resource
    Electronic Resource
    An immunohistochemical study of the extracellular matrix in oral squamous cell carcinoma and its association with invasive and metastatic potential (1994)
    Springer
    Virchows Archiv 424 (1994), S. 257-266 
    Details
    ISSN: 1432-2307
    Keywords: Extracellular matrix ; Immunohistochemistry ; Squamous cell carcinoma ; Invasiveness ; Metastasis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract The expression of extracellular matrices (ECMs) laminin (LN), type IV collagen (IV C), heparansulphate proteoglycan (HS-PG), fibronectin (FN), tenascin (TN), decorin and vitronectin (VN) was examined immunohistochemically in 112 primary tumours and 29 metastatic cervical lymph nodes in oral squamous cell carcinoma (OSCC). In highly invasive primary tumours, the expression of LN, IV C and HS-PG in the basement membrane along the tumour-stroma borderline and the expression of decorin and VN in the tumour stroma at the invasive site were all significantly decreased. The expression of FN and TN in the tumour stroma at the same site was markedly increased. In peritumour stroma in metastatic lymph nodes, LN, IV C, HS-PG, decorin and VN were weakly expressed, while FN and TN were strongly expressed. Thus, the staining pattern of the ECMs in the metastatic lymph nodes was similar to that in highly invasive primary tumours. Furthermore, in primary tumours of metastatic cases, the expression of LN, IV C, HS-PG, decorin and VN obviously decreased, while the expression of FN and TN increased when compared with those of the non-metastatic cases. The investigation of ECMs in OSCC was valuable in predicting tumour behaviour.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00194609
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