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  • 1990-1994  (1)
  • 1985-1989  (1)
  • 1
    Electronic Resource
    Electronic Resource
    IgE myelomatosis (1987)
    Springer
    Annals of hematology 55 (1987), S. 55-60 
    Details
    ISSN: 1432-0584
    Keywords: IgE myeloma ; Plasma cell leukaemia ; Monoclonal IgE gammopathy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary This paper describes a case of IgE (kappa) myeloma in a 39 year old female patient who has been observed for a period of eight years to the present. The findings and the course of disease in this patient were compared with 18 other case reports published since the discovery of IgE in 1966. In contrast to myelomas of other immunoglobulin classes, patients with IgE myelomas are somewhat younger and anaemia and hyperproteinaemia are more pronounced. A plasma cell leukaemia is more frequent and the ratio of light chains has shifted in favour of the kappa chains.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00319644
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Atypical chronic myelogenous leukemia in a patient with trisomy 8 mosaicism syndrome (1993)
    Springer
    Annals of hematology 66 (1993), S. 57-58 
    Details
    ISSN: 1432-0584
    Keywords: Chronic myelogenous leukemia ; Trisomy 8 ; Trisomy 8 mosaicism syndrome ; Constitutional disorders
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A 17-year-old woman was admitted for bone marrow transplantation with the diagnosis of atypical Philadelphia-negative chronic myelogenous leukemia (aCML), cytogenetically characterized by trisomy 8 as the sole chromosome aberration. A striking feature was a congenital opacity of the right cornea. Chromosomal analysis of skin fibroblasts were performed and revealed a mosaic for trisomy 8. Commonly, a distinct clinical picture leads to the diagnosis of trisomy 8 mosaicism syndrome (T8ms), but an extreme phenotypic variability has been observed. To our knowledge the development of an aCML in a patient with T8ms has not been reported. A review of the literature revealed that an association to other hematological disorders had been described in two cases. The question of whether our patient's aCML was a random event or not is discussed. The patient is now 24 months post transplant and shows no evidence of disease. Her Karnofsky score is 100%. We conclude that it might be worthwhile to look for an associated constitutional trisomy 8 mosaicism in all patients with trisomy 8 leukemia.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01737691
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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