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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Journal of intelligent manufacturing 4 (1993), S. 163-181 
    ISSN: 1572-8145
    Keywords: Module ; intelligent manufacturing system ; virtual factory ; task-oriented ; intelligent robot
    Source: Springer Online Journal Archives 1860-2000
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: This paper discusses requirements to be satisfied by future manufacturing systems and proposes a new concept of modular manufacturing to integrate intelligent and complex machines. In large-scale systems such as manufacturing systems, modularization is indispensable for clarifying logical structure and assuring a high degree of ease of construction. The parts, products and manufacturing equipments as well as the design and operating activities themselves are all described in units called modules. A manufacturing system is constructed and operated by combining these in building-block style. The creation of this manufacturing system relies on construction and operating systems that enable design and simulation in the virtual world, and production and control in the real world, in a unified approach. Hardware modules and software modules are compiled flexibly and hierarchically to fulfil specified tasks. A system in which modular manufacturing as a concept of system integration is applied to manufacturing robots is called a modular robot system. The robots are embedded in manufacturing systems as the highest application of model-based robotics.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1434-0879
    Keywords: LH-RH analogue ; Leuprolide acetate ; Cisplatin ; Mouse testis ; Spermatogenesis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The cytotoxic effect of cis-diamminedichloro-platinum II (cisplatin, CDDP) on spermatogenesis in BALB/C mice, and possible protection of the testes by leuprolide acetate (D-Leu-6 LHRH(1–9)-ethylamide, TAP-144, leuprolide), a synthetic gonadotropin-releasing hormone analogue, were examined. Temporary interruption of the pituitary-gonadal axis by the analogue and amelioration of the gonadal toxicity of cisplatin by reducing the cell division rate in spermatogenesis were expected. The results showed cisplatin to have a cytotoxic effect on spermatogenic cells in BALB/C mice. The administration of leuprolide had no effect on testicular weight or histological findings in the mouse testes. Pretreatment and simultaneous administration of leuprolide did not reduce the damaging effect of cisplatin on the testes in mice. This is at variance with a previously published report.
    Type of Medium: Electronic Resource
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