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  • 1990-1994  (3)
  • 1970-1974
  • microsphere  (2)
  • Experimental allergic encephalitis  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Targeting of adoptively transferred experimental allergic encephalitis lesion at the sites of Wallerian degeneration (1990)
    Springer
    Acta neuropathologica 80 (1990), S. 521-526 
    Details
    ISSN: 1432-0533
    Keywords: Major histocompatibility complex class II ; Wallerian degeneration ; Microglia ; Autoimmune disease ; Experimental allergic encephalitis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary To clarify the implication of the major histocompatibility complex class II (Ia) antigen induction in microglia following Wallerian degeneration in the central nervous system (CNS), experimental allergic encephalitis (EAE) was adoptively transferred to Lewis rats in which Ia antigens had been induced in microglia at the sites of Wallerian degeneration. In addition to randomly distributed typical EAE lesions, the recipient rats developed distinct inflammatory lesions in accord with the distribution of Ia-positive microglia; i.e., in the ipsilateral thalamus after cortical cryoinjury, and in the ipsilateral optic nerve, the contralateral optic tract and superior colliculus after unilateral eye ball enucleation. Thus, the EAE locus may be targeted by this approach. The inflammatory response was inducible by transfer of myelin basic protein-stimulated lymphocytes but not by transfer of phytohemagglutinin-stimulated or non-stimulated lymphocytes. When examined using monoclonal antibody surface markers; OX-6 for Ia antigen, W3/13 for pan T lymphocyte and OX-8 for cytotoxic/suppresser T lymphocyte, the types of lymphocytes in these lesions did not differ from those in ordinary EAE lesions in the spinal cord. The potential role of non-immunologically induced Ia-positive cell clusters that serve as a target for autoimmune CNS diseases was discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00294613
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Estimation of distribution of vinyl groups in micron-sized monodisperse polymer microspheres by bromine titration method (1991)
    Springer
    Colloid & polymer science 269 (1991), S. 1126-1132 
    Details
    ISSN: 1435-1536
    Keywords: Polymeremulsion ; microsphere ; vinylgroup ; brominetitration ; dispersionpolymerization ; seededpolymerization
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract The distribution of vinyl groups in polystyrene/poly(styrene-divinylbenzene) (PS/P(S-DVB)) composite microspheres produced by seeded copolymerization of S and DVB in the presence of 2.1-μm monodisperse PS seed particles was estimated from the amount detected with bromine titration method as a function of the reaction time under various conditions.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00654120
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    Preparation of micron-size monodisperse polymer microspheres having cationic groups (1992)
    Springer
    Colloid & polymer science 270 (1992), S. 733-737 
    Details
    ISSN: 1435-1536
    Keywords: Polymeremulsion ; microsphere ; chloromethylgroup ; polyamine ; cationicgroup ; dispersionpolymerization ; seededpolymerization
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: Abstract Micron-size monodisperse crosslinked polymer microspheres having chloromethyl groups were prepared by seeded copolymerization of styrene, divinylbenzene, and chloromethylstyrene in the presence of 2.1-μ monodisperse polystyrene seed particles produced by dispersion polymerization. The modification reaction of chloromethyl groups on the surfaces with polyamines such as triethylenetetramine and ethylenediamine was carried out. From the measurements of ξ potential and the amount of chloride ion released, the introduction of a large number of cationic groups at the surfaces was confirmed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00776143
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    Paper (German National Licenses)
    Fulltext
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