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  • 1990-1994  (2)
  • 1970-1974
  • fat malabsorption  (1)
  • immobilization  (1)
  • 1
    Electronic Resource
    Electronic Resource
    Duodenal pH in cystic fibrosis and its relationship to fat malabsorption (1990)
    Springer
    Digestive diseases and sciences 35 (1990), S. 1299-1304 
    Details
    ISSN: 1573-2568
    Keywords: cystic fibrosis ; pH ; fat malabsorption
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract To investigate the relationship between duodenal pH levels and supplemental pancreatic enzyme function in cystic fibrosis, 18 children with this condition had pH recordings performed from the second and fourth part of the duodenum. Compared to age-matched controls, patients with cystic fibrosis had significantly longer periods below a pH of 4.0 in the postprandial period and significantly less time above pH 5.8. These values correspond to the pH levels at which lipase is irreversibly destroyed (pH 4.0) and enteric coating of enzyme supplements dissolves (pH 5.8). A significant relationship was found between the pH recordings from the fourth part of the duodenum and the degree of residual fat malabsorption while taking enteric-coated enzyme supplements. Four patients with an excessively acidic duodenum and residual fat malabsorption despite high-dose enzyme supplementation were treated with misoprostol (Searle), a known acid-reducing agent. There were significant improvements in both duodenal pH values and fat absorption. We conclude that there is a wide range of duodenal pH values found in patients with cystic fibrosis and that the efficiency with which enzyme supplements work is closely related to these pH levels. Administration of misoprostol to those patients with excessively acidic duodenal pH levels as well as residual malabsorption appears to be of benefit in improving both the excessively acidic pH levels and the fat malabsorption.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01536423
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Mercury removal by immobilized algae in batch culture systems (1990)
    Springer
    Journal of applied phycology 2 (1990), S. 223-230 
    Details
    ISSN: 1573-5176
    Keywords: Chlorella ; immobilization ; mercury ; accumulation ; volatilization ; alginate
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract The accumulation and volatilization of mercury by non-immobilized and immobilizedChlorella emersonii have been studied in batch culture systems. Reduction in the mercury concentration in the growth medium by non-immobilized cells was highly dependent on inoculum density, whilst reduction in mercury concentration by immobilized cells was rapid at all inoculum densities. Mercury accumulation by immobilized cell biomass was significantly greater than by non-immobilized cells with 106 and 105 cells bead−1 or ml−1. Volatilization of mercury by non-immobilized cell systems was greatest at higher inoculum densities, whereas more mercury was volatilized from immobilized cell systems at lower inoculum densities, and was greatest with unstocked alginate beads. Thus, in immobilized systems, mercury removal from solution is complex and involves mercury accumulation by the cells and volatilization by the matrix and cells. Further studies of mercury accumulation and volatilization by unstocked immobilization matrices revealed that agarose volatilized much less mercury than alginate or agar. The precise mechanism of mercury volatilization by alginate remains unclear, though it is thought to be a chemical effect.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02179779
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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