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  • 1
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 68 (1990), S. 6327-6330 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: The results of neutron irradiation up to a fluence of 1023 m−2 (E〉0.1 MeV) are reported for sputtered NbN/AlN multilayer films. The superconducting properties change only slightly with neutron fluence. For the best multilayers, which exhibit critical current densities Jc of 〉108 A/m2 at 4.2 K and 20 T, the high-field data show virtually no change in Jc. It is therefore proved experimentally that NbN/AlN multilayers, which exhibit higher Jc than single NbN thin films, exhibit the same extremely radiation-hard, high-field behavior which was reported previously for such NbN films.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 69 (1991), S. 3172-3175 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Four types of differently prepared NbN films were irradiated at 4.6 K with fast neutrons to a fluence of 5.3 × 1022 m−2 (E(approximately-greater-than)0.1 MeV). The critical current densities Jc were measured in magnetic fields up to 23 T prior to irradiation, following low-temperature irradiation, and again after an annealing cycle to room temperature. In all films, Jc was found to be completely unchanged by the radiation and annealing treatments in fields up to 15 T, but to increase at higher magnetic fields. At the same time, the upper critical fields Bc2 increased by about 0.5 T (∼2%). Replotting Jc versus reduced field B/Bc2 leads to identical field dependencies also in the high-field range. Hence, the observed increase of Jc is equantitatively explained as a Bc2 effect.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Review of Scientific Instruments 65 (1994), S. 3574-3576 
    ISSN: 1089-7623
    Source: AIP Digital Archive
    Topics: Physics , Electrical Engineering, Measurement and Control Technology
    Notes: We have designed a probe to rotate a sample around two independent axes in a magnetic field of up to 8 T and at temperatures varying from 3 K to room temperature. The sample is in very good thermal contact with a thermometer and a regulated heater, enabling precise temperature control. Pogo pins enable quick electrical connections to the sample. Two computer-controlled stepper motors rotate the sample around the two independent axes. This probe was primarily designed to investigate the anisotropy of the critical currents of superconducting thin films in a magnetic field.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    Archives of gynecology and obstetrics 217 (1974), S. 443-454 
    ISSN: 1432-0711
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Nach den vorliegenden Untersuchungen weisen Patientinnen mit chronischer Kolpitis eine Stimulation des Zellzyklus auf, die denen mit Carcinoma in situ oder invasivem Karzinom vergleichbar ist. Photometrische Messungen an Smears zeigten in diesen Fällen über die Norm hinaus erhöhte DNS-Werte und davon abhängig vermehrt atypische RNS- und Histon-Mengen. Desgleichen war der Heterochromatinanteil im Zellkern erhöht. Ähnliche Befunde fehlten bei Patientinnen unter Ovulationshemmern und in den Kontrollfällen.
    Notes: Abstract The increasing use of ovulation inhibitors in human society raises the question of their carcinogenic effect. Therefore vaginal smears of patient taking the pill over a long period were compared with smears showing histologically chronic inflammation, carcinoma in situ or invasive cancer of the cervix uteri. Dryweight and its concentration was determined on native cells using interference microscopy. After fixation and staining the values of DNA, RNA and Histones of the nucleus were measured by microscope photometer. The planimetric analysis of simultaneously taken microphotographs yields the amount of heterochromatin. All results were put in diagrams and compared one with another. Thus we found, that the changes in cell metabolism caused by the pill are not comparable to them in carcinoma in situ or invasive cancer of the human portio uteri.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Archives of gynecology and obstetrics 217 (1974), S. 437-441 
    ISSN: 1432-0711
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Nach enzymatischer Aufarbeitung zytologischer Abstriche ließ sich die basische Aminosäure Arginin mit Ninhydrin anfärben. Die durch Blaulicht angeregte Fluoreszenz wurde zytophotometrisch gemessen und die Verteilung der Arginin-Mengen mit der des Histons verglichen. Auch im Rahmen der Karzinogenese, die mit einer DNS-Vermehrung und Heterochromatisierung einhergeht, konnten dabei keine Unterschiede gefunden werden. Dem Arginin-reichen Histon wird daher eine direkte Beteiligung an der DNS-Synthese zugesprochen.
    Notes: Abstract After enzymolysis of vaginal smears the basic amino acid arginine in the nucleus was stained with ninhydrine. The fluorescence caused by blue-light cytophotometrically was determined and the distribution of arginine values was compared with those of histone. Also during carcinogenesis accompanied by augmentation of DNA and heterochromatin no differences were found. We therefore mean, that arginine rich histone in directly participated in synthesis of DNA.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Research in experimental medicine 164 (1974), S. 151-156 
    ISSN: 1433-8580
    Keywords: DNA ; Heterochromatin ; Experimental cancer of large intestine Rat ; DNS ; Heterochromatin ; Experimentelles Dickdarmcarcinom ; Ratte
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Maligne Tumoren zeichnen sich durch einen von der Norm abweichenden DNS-Gehalt und einen erhöhten Heterochromatinanteil im Zellkern aus. Im Rahmen der experimentellen Carcinogenese am Colon der Ratte mit 1,2-Dimethylhydrazin lassen sich diese Befunde neben dem Carcinom und dem maligne entarteten Polypen auch beim benignen Polypen und beim sog. Carcinomain situ bei sonst unauffälliger Schleimhaut nachweisen. Es handelt sich bei ihnen daher um echte Vorstufen des Carcinoms.
    Notes: Summary Malignant tumours are determined by an atypical amount of DNA and an in increased part of heterochromatin in the nucleus. In the experimental carcinogenesis in the colon of rats with 1,2-dimethylhydrazine these results were found in addition to the carcinoma and the malignant polypus in the benign polypus and in the s.c. carcinomain situ too. Therefore they are regarded as real precursors of this cancer.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Pharmacy world & science 15 (1993), S. 105-115 
    ISSN: 1573-739X
    Keywords: Calcium phosphates ; Drug compounding ; Excipients ; Particle size ; Physics ; Powders ; Tablets
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract Ten commercially available calcium phosphates used for direct tableting were evaluated. The particle size distributions, powder properties, Sorption isotherms and pH values of aqueous slurries were compared. All samples showed good or at least sufficient flowability. Scanning electron micrographs illustrated the different kinds of manufacturing and gave hints on their expectable behaviour under compaction pressure. The sorption isotherms of identical chemical substances, which had been manufactured by different methods, differed strongly. This can be related to their specific surface areas. Most of the hydroxylapatites have large surface areas and can absorb up to more than 15% water at 93% relative humidity. Dibasic calcium phosphate dihydrate was non-hygroscopic and absorbed less than 1% water. With the exception of monobasic calcium phosphate monohydrate all calcium phosphates behaved quite neutral in water. Monobasic calcium phosphate monohydrate can be regarded as a solid acid. Although the calcium phosphates are usually stable substances, the role of crystal water in the case of dibasic calcium phosphate dihydrate and monobasic calcium phosphate monohydrate is problematic due to possible interactions with active ingredients.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Springer
    Pharmacy world & science 15 (1993), S. 116-122 
    ISSN: 1573-739X
    Keywords: Calcium phosphates ; Drug compounding ; Ejection force ; Excipients ; Friability ; Hecket plots ; Lubrication ; Particle size ; Powders ; Tablets ; Tensile strength
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstracts Ten calcium phosphates suitable for direct compression (dibasic calcium phosphate dihydrate, dibasic calcium phosphate anhydrous and hydroxylapatite) were investigated with respect to their compressional behaviour. Except for Di-Cafos A all products gave tablets with sufficient to good mechanical strength. Nevertheless, there were differences between the products. All tablets prepared from the different products showed a high friability. This seems to be a problem of the calcium phosphates in general. On the other hand, the influence of magnesium stearate on the mechanical strength of the tablets was negligible for all products investigated. Moreover, a considerable effect of the particle size on the tensile strength of the tablets was found. The ejection forces and residual pressures were high in general, but critical only in the case of hydroxylapatites. Heckel plots were used to differentiate between plastic deformation and brittle fracture of the particles. In the case of calcium phosphates the slope of the Heckel plots indicated the hardness of the particles rather than their deformation behaviour.
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Basic research in cardiology 62 (1970), S. 72-90 
    ISSN: 1435-1803
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Hitherto valuation of coronary sclerosis generally depended on a personal statement-mostly it was subjective. This passes for the most categorizations as I.–IV. degree or slight, middle-severe, severe a.s.o. Therefore publications, dealing with the severeness of coronary sclerosis, scarcely are comparable. Now a simple graduation of coronary sclerosis is proposed, which doesn't only consider the loss of orifice, but receives the haemodynamic value of the single boughs and the vascular lengths into a common valuation number too. Thisvaluation number (Bewertungszahl) is of following composition (Fig. 1): Stenosis counts 1 point, occlusion 5 points. Then this points get multiplied with the haemodynamic value points for vascular length, type of supply and aortic ostium. The haemodynamic effect of coronary sclerosis can't be described completely by the valuation numbers alone (see Fig. 8 and 13). The haemodynamic value of coronary sclerosis is only perceptible in relation to weight of the heart (clinical: size, degree of hypertrophy, blood-pressure). Coronary diseases can depend only on the heart weight, when the weight for instance reaches or oversteps the limit of about 1500 grs. To cause a coronary disease, coronary sclerosis commonly must be more severe at a lower than at a higher heart weight. Therefore, if all other factors which can lead to a coronary disease are neglected in this context, coronary diseases depend on coronary sclerosisand heart weight. This basis of valuation and valuation numbers can be applied to the analysis of intravital angiograms. The choice of 1 point for stenosis and 5 points for occlusion permits a further distinction of orifice deminuation with the points 2–4 special inquiries.
    Notes: Zusammenfassung Die Bewertung der Koronarsklerose stützte sich bisher im wesentlichen auf ein persönliches Urteil-sie ist also meist subjektiv. Das gilt für die meisten Einstufungen wie I.–IV. Grades oder leicht, mittelschwer oder schwer usw. Deshalb sind bisher Arbeiten, die sich mit der Schwere der Koronarsklerose beschäftigen, kaum miteinander vergleichbar. Es wird nun eine einfache Graduierung der Koronarsklerose vorgelegt, die nicht nur den Lichtungsverlust berücksichtigt, sondern auch die hämodynamische Wertigkeit der einzelnen Äste und Gefäßstrecken in eine Bewertungszahl aufnimmt. DieBewertungszahl setzt sich folgendermaßen zusammen (Abb. 1). Stenosen erhalten einen Punkt, Verschlüsse fünf Punkte. Die Punkte werden dann mit den hämodynamisch gewerteten Punkten für Gefäßstrecke, Versorgungstyp und aortale Ostien multipliziert. Die Bewertungszahlen der Koronarsklerose allein (vgl. Abb. 8 und 13) geben ihren hämodynamischen Effekt nicht vollständig wieder. Die hämodynamische Wertigkeit der Koronarsklerose ist nur in Bezug auf das Herzgewicht (klinisch: Herzgröße, Grad der Hypertrophie, Blutdruck) erkennbar. Koronarleiden können nämlich in dem Falle nur auf der Herzhypertrophie beruhen, wenn zu. B. das Herzgrenzgewicht ∼ 1500 g erreicht oder überschritten wird. Im allgemeinen muß bei niedrigem Herzgewicht die Koronarsklerose schwerer sein, um ein Koronarleiden hervorzurufen, als bei einem höheren Herzgewicht. Koronarleiden sind also von Koronarsklerose und Herzgewicht abhängig, wenn wir in diesem Zusammenhang alle anderen Faktoren, die zu einer Koronarkrankheit führen können, außer Acht lassen. Die Bewertungsgrundlagen und- zahlen sind ohne weiteres auf die Auswertung intravitaler Angiogramme zu übertragen. Die Wahl der Punktezahl 1 für die Stenose und 5 für den Verschluß erlaub für spezielle Untersuchungen eine weitere Differenzierung des Lichtungsverlustes mit den Zahlen 2–4.
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