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  • 1990-1994  (2)
  • 1965-1969
  • 1935-1939
  • Carbohydrate metabolism  (1)
  • Characterization  (1)
Materialart
Erscheinungszeitraum
  • 1990-1994  (2)
  • 1965-1969
  • 1935-1939
Jahr
  • 1
    Digitale Medien
    Digitale Medien
    Springer
    Annals of the Institute of Statistical Mathematics 46 (1994), S. 351-360 
    ISSN: 1572-9052
    Schlagwort(e): Characterization ; exponential distribution ; gamma distribution ; geometric distribution ; Poisson process ; renewal process
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Mathematik
    Notizen: Abstract Given two independent positive random variables, under some minor conditions, it is known that fromE(Xr∥X+Y)=a(X+Y)r andE(Xs∥X+Y)=b(X+Y)s, for certain pairs ofr ands, wherea andb are two constants, we can characterizeX andY to have gamma distributions. Inspired by this, in this article we will characterize the Poisson process among the class of renewal processes via two conditional moments. More precisely, let {A(t), t≥0} be a renewal process, with {S k, k≥1} the sequence of arrival times, andF the common distribution function of the inter-arrival times. We prove that for some fixedn andk, k≤n, ifE(S k r ∥A(t)=n)=atr andE(S k s ∥A(t)=n)=bts, for certain pairs ofr ands, wherea andb are independent oft, then {A(t), t≥0} has to be a Poisson process. We also give some corresponding results about characterizingFto be geometric whenF is discrete.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Digitale Medien
    Digitale Medien
    Springer
    Archives of toxicology 66 (1992), S. 646-651 
    ISSN: 1432-0738
    Schlagwort(e): Sodium dichromate ; Nephrotoxicity ; Glutathione ; Ascorbate ; Carbohydrate metabolism
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Medizin
    Notizen: Abstract Ascorbate treatment 30 min prior to sodium dichromate (20 or 30 mg/kg, s.c.) shows higher potency than that of glutathione (GSH) in protecting against both the metabolic disturbance and nephrotoxicity induced by dichromate. However, ascorbate treatment after 2 h of dichromate intoxication had no effect on dichromate-induced blood urea nitrogen (BUN) elevation 3 days after intoxication. In contrast, dichromate-induced glucosuria, which reached maximum levels at 3 days after treatment, was significantly decreased by GSH or N-acetyl cysteine (NAC) treatment, even if its administration was after 24 h of dichromate intoxication. Pretreatment with GSH depletors such as diethyl maleate (DEM) and buthionine sulfoximine (BSO) had no effect on dichromate-induced nephrotoxicity. GSH levels in the liver and kidney were not affected at 3 h after dichromate treatment. However, dichromate significantly increased tissue GSH levels with a marked increase in liver per kidney GSH ratio at 24 h after treatment, if food was withheld subsequent to dichromate treatment, indicating that GSH biosynthesis resulted from the accelerated protein breakdown. These results suggest that GSH-mediated dichromate reduction is not a kinetically favorable pathway in vivo; however, GSH plays an important role in protection against dichromate-induced nephrotoxicity. In addition, the cellular metabolism of dichromate in the early period after treatment is important in the pathogenesis of its nephrotoxicity.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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