ISSN:
1573-8353
Source:
Springer Online Journal Archives 1860-2000
Topics:
Chemistry and Pharmacology
Notes:
Abstract A number of 1-butyl-3-aminoaklyl-4-methyl-7-azaindoles are synthesized, viz. 1-butyl-4-methyl-7-azatryptamine, 1-butyl-3-aminomethyl-4-methyl-7-azaindole, and 1-butyl-3-dimethylaminomethyl-4-methyl-7-azaindole (1-butyl-4-methyl-7-azagramine). It is shown, using butylamine, that aliphatic primary amines behave differently in the reaction with trichlorocollidine from aromatic amines, and similarly to ammonia. The reaction product from trichlorocollidine and butylamine (as well as dibutylamine) is 1-butyl-4-methyl-6-chloro-7-azaindoline. Tributylamine is isolated from among the products of reaction of trichlorocollidine with dibutylamine, and the mechanism of its formation is considered.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00955596
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