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  • 1990-1994  (3)
  • 1960-1964  (10)
  • 1
    Electronic Resource
    Electronic Resource
    Regeneration of olfactory paths in carp (Cyprinus carpio L.) (1964)
    Springer
    Cellular and molecular life sciences 20 (1964), S. 519-520 
    Details
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Zusammenfassung Wie mit einer neuentwickelten Methode gezeigt werden konnte, erlangen Karpfen 40 Tage nach Durchschneidung der Olfaktoriusbahnen wieder weitgehende Riechfähigkeit. Auch histologisch tritt Regeneration ein.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02154089
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Oculovestibular interactions under microgravity (1993)
    Springer
    Journal of molecular medicine 71 (1993), S. 749-756 
    Details
    ISSN: 1432-1440
    Keywords: Visual vestibular interaction ; Ocular counterrotation ; Afterimage method ; Luminous line ; Neck position receptors
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary On a space mission in March 1992 a set of experiments were performed aimed at clarifying the interaction between visual, proprioceptive and vestibular inputs to the equilibrium system. Using the VESTA goggle facility from the European Space Agency we investigated the effect of pure neck receptor stimulation on eye position as measured by the flash afterimage method and on perception of a head-fixed luminous line in space. Space vestibular adaptation processes were measured by rotating pattern perception during prescribed head movements. It was found that static ocular counterrotation does not occur under micro gravity conditions. This result suggests that the neck receptors apparently do not contribute to a measurable extent. The subjective orientation of a vertical line was perceived correctly inflight. Obviously neck receptors on the perception level can fully substitute for the ineffective equilibrium organs of the inner ear within less than 4 days. The rotating pattern perception during different head motion patterns is not influenced by the absence of a gravity reference.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00209730
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Responses to eccentric rotation in two space-bound subjects (1993)
    Springer
    Journal of molecular medicine 71 (1993), S. 757-760 
    Details
    ISSN: 1432-1440
    Keywords: Rotating chair ; Otolith ; Vestibular system ; Asymmetry ; Human
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Two subjects were rotated eccentrically in the manner described previously. In contrast to a normal control group, settings of a luminous line to the subjective vertical were almost unrelated to the gravitoinertial vector before, and totally so shortly after, space flight. Only 3 days postflight did a clear relation to the gravitoinertial vector re-establish itself in the one subject who actually flew. The correspondence became normal 5 days after the flight. Since there were no clinical abnormalities evident in the subjects, it is suggested that both subjects suppressed their vestibular information, presumably as an effect of vestibular deconditioning training before the flight. In addition, as a consequence of the flight experience one subject continued to ignore it several days after the flight.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00209731
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Response of individual olfactory nerve cells to microelectrophoretically administered chemical substances (1963)
    Springer
    Pflügers Archiv 277 (1963), S. 125-140 
    Details
    ISSN: 1432-2013
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00363371
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    Paper (German National Licenses)
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  • 5
    Electronic Resource
    Electronic Resource
    Lokalisierung absteigender Atmungsbahnen im Rückenmark der Katze mittels antidromer Reizung (1964)
    Springer
    Pflügers Archiv 281 (1964), S. 231-244 
    Details
    ISSN: 1432-2013
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung 1. Sowohl inspiratorische als auch exspiratorische Nervenzellen innerhalb der gleichbenannten Areale der Medulla oblongata rostral und caudal des Obex senden direkte Axone herunter ins Rückenmark. 2. Die Mehrzahl der absteigenden inspiratorischen Fasern kreuzt in der unteren Medulla oblongata auf die Gegenseite, der Rest verläuft ipsilateral. Die ungekreuzten inspiratorischen Fasern finden sich diffus verteilt im ventralen Teil des Seitenstranges und dorsalen Teil des Vorderseitenstranges. Die exspiratorischen Fasern kreuzen fast alle und ziehen dann im Tractus reticulospinalis des Vorderseitenstranges der Gegenseite caudalwärts. Bilaterale Axon-Kollateralen fanden sich nie. 3. Die durchschnittliche Leitungsgeschwindigkeit der absteigenden respiratorischen Fasern des Rückenmarkes beträgt 40 m/sec. 4. Inspiratorische R-α- und R-β-Neurone haben direkte spinale Projektionen. 5. Inspiratorische Nervenzellen, deren Axone ipsilateral descendieren, können in der Medulla oblongata unmittelbar benachbart zu inspiratorischen Nervenzellen mit kontralateral descendierenden Axonen sein.
    Notes: Abstract 1. Inspiratory and expiratory nerve cells located in the corresponding zones within the medulla oblongata rostral and caudal to the obex have their axons descending directly in the spinal cord. 2. The majority of the descending inspiratory fibres cross in the lower part of the medulla oblongata to the opposite side; the rest descends ipsilaterally. Of the crossed and uncrossed inspiratory fibers, most are found diffusely distributed throughout the ventral side of the lateral column and the dorsolateral part of the ventral column. Almost all expiratory fibers cross in the lower part of the medulla oblongata and then descend caudally with the tractus reticulospinalis situated in the dorsolateral part of the ventral column. We found no bilateral axon collaterals of any respiratory neurone. 3. The main conduction velocity of the descending respiratory fibers of the spinal cord was 40 m/sec. 4. Inspiratory R-α- as well as R-β-neurones have spinally descending axons. 5. Inspiratory nerve cells with ipsilaterally descending axons are situated in the intimate neighbourhood of those with contralaterally descending axons.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00412424
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    Paper (German National Licenses)
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  • 6
    Electronic Resource
    Electronic Resource
    Untersuchungen zur Lokalisation der medullären Kreislaufzentren: Über ein Prädilektionsgebiet kardiovasculärer Neurone im Rautenhirn der Katze (1961)
    Springer
    Pflügers Archiv 274 (1961), S. 53-53 
    Details
    ISSN: 1432-2013
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02292280
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    Paper (German National Licenses)
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  • 7
    Electronic Resource
    Electronic Resource
    Hemmungsmechanismen im Bulbus olfactorius (1963)
    Springer
    Pflügers Archiv 278 (1963), S. 76-77 
    Details
    ISSN: 1432-2013
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00672585
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  • 8
    Electronic Resource
    Electronic Resource
    Spontane und reizbedingte Änderungen der antidromen Erregbarkeit von bulbären respiratorischen Nervenzellen der Katze (1964)
    Springer
    Pflügers Archiv 281 (1964), S. 245-258 
    Details
    ISSN: 1432-2013
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung 1. Die Erregbarkeit inspiratorischer und exspiratorischer Neurone der Medulla oblongata ist, gemessen an ihrer antidromen Invasionsbereitschaft, am größten während der spontanen Entladungsperioden, weniger groß unmittelbar vor und am kleinsten nach den Entladungsperioden. 2. Während der Hyperventilationsapnoe ist die Erregbarkeit an den von uns geprüften inspiratorischen Neuronen deutlich größer als während der Atempause zwischen zwei spontanen respiratorischen Entladungsperioden. 3. Durch Erhöhung der Reizstärke an den absteigenden Atmungsbahnen im Rückenmark gelingt es, zusätzliche antidrome Entladungen auch in den Atempausen auszulösen. Dies kann durch fördernde synaptische Querverbindungen zwischen den Atmungsneuronen erklärt werden. 4. Antidrome Reizung exspiratorischer Neurone führt zu kurzfristiger Hemmung der inspiratorischen Neurone. Dieser Befund wird mit der reziproken Innervation inspiratorischer und exspiratorischer Neurone über Axonkollateralen erklärt. 5. Bei antidromer Reizung mit frequenten Impulsen, sowie auch bei niederfrequenter Reizung in den Intervallen zwischen den spontanen Entladungsperioden tendieren respiratorische Zell-Aktionspotentiale besonders leicht zur „Disintegration“, Latenzzeitverlängerung und periodischer Gruppenbildung.
    Notes: Abstract 1. The excitability of inspiratory and expiratory neurones in the medulla oblongata was measured by means of their facility to be invaded antidromically. Their antidromic excitability was found to be greatest during periods of spontaneous discharging, less immediately before, and least immediately after such discharge period. 2. The antidromic excitability of the tested inspiratory neurones was markedly increased during hyperventilation apnoea, compared with that during the pause between two spontaneous respiratory discharge periods. 3. It is possible to trigger additional antidromic discharges even in the respiratory pauses by augmenting the stimulation voltage applied to the descending respiratory pathway. This may be explained by facilitating synaptic interconnections between the respiratory neurones. 4. Antidromic stimulation of expiratory neurones brings about transient inhibition of inspiratory neurones. This finding may best be explained by reciprocal innervation of inspiratory and expiratory neurones by axon collaterals. 5. Action potentials from medullary respiratory nerve cells tended easily to disintegrate into their “A” and “B” fractions when antidromic tetanization was applied. They also showed prolongation of their latencies and a tendency for periodic following and failing to follow the antidromic stimuli.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00412425
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  • 9
    Electronic Resource
    Electronic Resource
    Hepatitis C virus (HCV) genotype distribution in German isolates: studies on the sequence variability in the E2 and NS5 region (1994)
    Springer
    Archives of virology 139 (1994), S. 379-388 
    Details
    ISSN: 1432-8798
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We report on molecular characterization of hepatitis C virus (HCV) isolates in intravenous drug abusers, as compared to non-drug using patients with posttransfusion hepatitis or sporadic hepatitis of unknown origin. Virus typing was performed by RFLP analysis of PCR products in the 5′ NCR. Subtyping was done by hybridization with subtype specific probes or by sequencing in the NS4 and NS5 region, respectively. HCV subtype 1b was found most commonly among all the isolates. However, the subtype 3a had a high prevalence (about 46%) in the group of drug addicts. In these subtype 3a isolates the N-terminal part of the E2 protein was highly variable. This confirms the presence of a hypervariable region (HVR1) in this envelope protein found in all hepatitis C viruses. Each subtype 3a isolate examined had a characteristic unique hypervariable region in the E2 protein. It is noteworthy that there are four amino acids in this region which were highly conserved between all HCV sequences published. It can be assumed that such conserved amino acids are significant for structure and function of this viral protein. In our HCV subtype 3a isolates the NS5 sequences were highly conserved.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01310799
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    Paper (German National Licenses)
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  • 10
    Electronic Resource
    Electronic Resource
    Beitrag zur Technik der extra- und intracellulären, sowie der stereotaktischen Mikroableitung im Gehirn (1960)
    Springer
    Pflügers Archiv 271 (1960), S. 245-256 
    Details
    ISSN: 1432-2013
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary 1. A method for preparation of glass insulated and sharpened platinum-wire-microelectrodes is outlined. 2. Some experiences of our laboratory in preparing and using capillary microelectrodes are given. A method for avoiding brain pulsation during intracellular recording is reported. 3. A headsupport with a microdrive especially adapted for microrecording and a new apparatus for stereotaxic microrecording are described. 4. A new method for marking the site of recording with capillary or metallic electrodes is suggested. It is based on the photographic reduction of silver at small metallic deposits in the tissue. 5. A critical consideration is given to the interpretation possibilities of microrecording in the brain.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00363007
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    Paper (German National Licenses)
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