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  • 1990-1994  (2)
  • 1955-1959  (2)
  • 1
    Electronic Resource
    Electronic Resource
    Grating spectrograph in InGaAsP/InP for dense wavelength division multiplexing (1991)
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 59 (1991), S. 627-629 
    Details
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A grating spectrograph in InGaAsP/InP suitable for use in the wavelength region from 1.2 to 1.6 μm is presented. Experiments for devices with a channel spacing of 3.7 nm and more than 30 channels between 1.48 and 1.59 μm are described. The measured cross talk level is below −25 dB. The devices have only very low polarization sensitivity. This spectrograph is suited for monolithic integration with photodiodes, laser diodes, or optical amplifiers on a single chip.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.105405
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Therapeutic concentrations of lithium and carbamazepine inhibit cGMP accumulation in human lymphocytes (1991)
    Springer
    Psychopharmacology 104 (1991), S. 45-50 
    Details
    ISSN: 1432-2072
    Keywords: Lithium ; Carbamazepine ; Guanylate cyclase ; Lymphocytes ; Mechanism of action
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Although a large variety of biochemical effects have been reported for lithium (Li) and carbamazepine (Cbm), the final molecular mechanism underlying their therapeutic efficacy for recurrent affective disorders is still unknown. The data presented here clearly indicate that therapeutic concentrations of both drugs inhibit sodium nitroprusside-induced accumulation of cGMP in human lymphocytes to about the same extent. The effect is not seen for other antidepressants, and shows pronounced interindividual variations in healthy volunteers. A similar effect of lithium and carbamazepine can also be demonstrated for the cGMP accumulation of central neurons using the model of dissociated cells of the mouse brain. The results are discussed in view of a common mechanism of action of both drugs. Furthermore, it is speculated that the individual sensitivity of the cGMP generating system of human lymphocytes to both drugs might be used to predict therapeutic response or nonresponse of the individual patient.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02244552
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Zur Bedeutung der Lipase bei der Tuberkulose (1959)
    Springer
    Lung 119 (1959), S. 439-445 
    Details
    ISSN: 1432-1750
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Zusammenfassung In 294 Einzeluntersuchungen wurden Bestimmungen des Blutlipasespiegels bei Tb-negativen und Tb-positiven Tieren vorgenommen. Die Auswahl der Tiere erfolgte in der Weise, daß bei Tieren mit Neigung zu produktiven Tuberkuloseformen, zum andern bei Tieren mit überwiegend exsudativer Tuberkulose Blutproben entnommen wurden. Dabei konnte festgestellt werden, daß die erstgenannten Tierarten einen höheren normalen Blutlipasetiter besitzen als letztere. Im Falle einer Tb-Infektion besitzen diese Tierarten dadurch eine günstigere Resistenzlage, die auch in dem produktiven Verlauf der Tuberkulose zum Ausdruck kommt. Tierarten mit exsudativen Verlaufsformen haben demgegenüber einen niedrigeren Lipasespiegel. Bei Tuberkulose jedoch kommt es zu einem Anstieg der Lipaseaktivität, was als Abwehrreaktion des Organismus gedeutet wird. Die außerordentliche Streuung der Lipasewerte läßt vermuten, daß neben dieser tierartlichen Eigentümlichkeit ein individuelles Fettspaltungsvermögen den weiteren Verlauf der Tb-Infektion beeinflußt.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02149301
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    Paper (German National Licenses)
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  • 4
    Electronic Resource
    Electronic Resource
    Untersuchungen zur Wirksamkeit der Lungenlipase von Pferd und Rind auf das Mycobacterium tuberculosis (1959)
    Springer
    Naturwissenschaften 46 (1959), S. 209-210 
    Details
    ISSN: 1432-1904
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Natural Sciences in General
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00632585
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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