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  • 1990-1994  (4)
  • 1950-1954
  • 1925-1929
  • Analytical Chemistry and Spectroscopy  (3)
  • Basal cells  (1)
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Year
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Protoplasma 159 (1990), S. 77-84 
    ISSN: 1615-6102
    Keywords: Stem cells ; Phenotypic markers ; Proliferation potential ; Keratins ; Basal cells ; Preneoplasias ; Development
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary The evidence for mammary epithelial stem cells and their phenotypic characteristics in normal and neoplastic development is reviewed. The presence of stem cells in all parts of the mammary parenchyma at all stages of differentiation has been demonstrated by transplantation experiments. The phenotypic characterization of stem cells has been defined by a battery of monospecific antibodies. These studies suggest that a mammary epithelium stem cell compartment exists in the basal layer of the gland as well as in the end bud. Whether these same stem cells are expressed in mammary preneoplasias and neoplasias has not been answered conclusively. Phenotypic markers specific for stem cells and stably expressed in transformed cell populations are needed to follow the fate of stem cells.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 0951-4198
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Physics
    Notes: The use of a laser-desorption mass spectrometer to examine a coal liquefaction extract known to contain high-molecular-mass material (from size-exclusion chromatography) has shown the presence of components of molecular mass in excess of 104Da for the first time. The molecules detected differ from each other in molecular mass by a few hundred or a few thousand Da. These preliminary results indicate that the basic coal-structure molecules probably consist of aromatic clusters on a chin, in reasonable agreement with current theories of coal structure.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 0951-4198
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Physics
    Notes: Molecular masses up to 270 000 u have been observed during matrix-assisted laser desorption mass spectroscopy on a sample of bituminous coal; the major fraction of desorbed ions appeared between m/z values of 800 and 5000. Similar mass distributions have been found in a coal-liquefaction extract and a pyrolysis tar. The highest molecular masses identified in this work far exceed previously reported high molecular masses found in coal-derived products (12 000 u), which were also detected by laser-desorption mass spectrometry.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Rapid Communications in Mass Spectrometry 7 (1993), S. 360-362 
    ISSN: 0951-4198
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Physics
    Notes: The production of carbon clusters (but not fullerenes) from coal-derived material by the use of laser desorption mass spectrometry is described. Benzo(e)pyrene, a standard polynuclear hydrocarbon found in coal tars, also gave carbon clusters despite using low laser power to avoid pyrolysis of target molecules. Positive- and negative-ion spectra of the standard included carbon clusters. These clusters are formed by the laser energy and can be confused with aromatic hydrocarbons of the same nominal masses. They have no relevance for studies of coal structure.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
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