ISSN:
1573-7225
Keywords:
Childhood leukemia
;
electric and magnetic fields
;
electricity delivery equipment
;
electromagnetics
;
epidemiologic methods
;
lymphoma
;
meta-analysis
;
nervous system tumors
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract In 1979, Wertheimer and Leeper reported an increased risk of cancer mortality among children living near ‘electrical wiring configurations’, suggestive of high current flow. Since then, numerous, often inconclusively small, investigations with conflicting results have studied the possible asociation between exposure to electric and magnetic fields (EMF) and health effects. The high prevalence of exposure to EMF has drawn attention to the issue of carcinogenesis. We report here the results of a meta-analysis of 13 epidemiologic studies of residential proximity to electricity transmission and distribution equipment and risk of childhood leukemia, lymphoma, and nervous system tumors. The combined relative risks for leukemia, lymphoma, and nervous system tumors are 1.49 (95 percent confidence interval [CI]=1.11–2.00); 1.58 (CI=0.91–2.76); and 1.89 (CI=1.34–2.67) respectively. The reports of the primary studies were evaluated for epidemiologic quality and adequacy of exposure assessment. We found no statistically significant relation between combined relative risk estimates and 15 indicators of epidemiologic quality. Assessment of EMF exposure in the primary studies was found to be imperfect and imprecise. Additional high quality epidemiologic research, incorporating comprehensive assessments of EMF exposure collected concurrently with surrogate measures of exposure, is needed to confirm these results.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01804980
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