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  • 1990-1994  (2)
  • 1940-1944
  • Buspirone  (1)
  • birefringence  (1)
Material
Years
  • 1990-1994  (2)
  • 1940-1944
Year
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Psychopharmacology 104 (1991), S. 91-96 
    ISSN: 1432-2072
    Keywords: Buspirone ; Smokers ; Withdrawal
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract This paper reports on a double blind trial of the effect of buspirone, 15 mg per day, on cigarette withdrawal symptoms and ability of smokers to maintain abstinence during treatment. A total of 61 smokers were randomly assigned to active or placebo conditions. They were maintained on their drug for 2 weeks prior to attempting abstinence and then for a further 4 weeks of abstinence. Subjects attended weekly group sessions of a psychological treatment programme. There was no evidence that the side effects in the active drug group were worse than those in the placebo group. Although there was no significant difference between active and placebo conditions on withdrawal symptoms, smokers in the active drug condition were more than twice as likely to maintain abstinence for the duration of the study than those in the placebo condition (47% versus 16%, chi square = 5.3,P〈0.025). The results provide preliminary evidence for short-term efficacy of buspirone as an aid to smoking cessation at a low dose. They also provide evidence of a dissociation between withdrawal symptoms and successful abstinence.
    Type of Medium: Electronic Resource
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Journal of inorganic and organometallic polymers and materials 2 (1992), S. 29-45 
    ISSN: 1572-8870
    Keywords: Polysilenes ; polysilanes ; liquid crystals ; mesophases ; birefringence
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract (I) Ordered and disordered polysilane copolymers: Condensation of ClSiMe2Si(n-Hex)2SiMe2Cl with Na/K in toluene at 90°C produced a polymer with a strongly bimodal molecular weight distribution. The high-M w and low-M w portions were separated by fractional precipitation with 2-propanol, and the properties of the two fractions were investigated.29Si-NMR spectra show that the low-M w fraction is fully ordered but the high-M w fraction is randomized. (II) Liquid crystalline polysilanes: Condensation ofn-Bu(n-Hex)SiCl2 with Na in toluene led to a homopolymer which is a rubbery solid at 25°C. The polymer undergoes a second-order transition at −45°C and a first-order (melt) transition at −20°C. X-ray diffraction shows that the polymer has the same structure, a columnar hexagonal lattice, in all three phases; from −20 to 〉200°C, it exists in a columnar liquid crystalline mesophase. Similar hexagonal mesophases were observed at 25°C for the family of copolymers, (n-Hex2Si) n (Alk2Si) m , Alk =n-Pentyl,n-Bu,n-Pr, Et, Me.
    Type of Medium: Electronic Resource
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