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  • 1
    Electronic Resource
    Electronic Resource
    Springer
    European journal of nuclear medicine 17 (1990), S. 369-371 
    ISSN: 1619-7089
    Keywords: Bone scan ; Red blood cell scan ; Epidermal naevus syndrome ; Haemangiomas of bone ; Hypophosphataemic osteomalacia
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A bone scan and red blood cell scan in the rare epidermal naevus syndrome, associated with multiple haemangiomas of the bone and hypophosphataemic osteomalacia in a 20-year-old man are reported. The typical pattern of osteomalacia on the bone scan was associated with lesions of increased bone metabolism in the peripheral bones. The haemangiomas did not pool labelled red blood cells. Thus, the bone scan seems to be suitable for diagnosing the complete extent of haemangiomas in bone, but they could not be specifically proven by red blood cell pooling.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1619-7089
    Keywords: Iodine-123-Tyr-Octreotide ; Somatostatin receptors ; In vivo ; In vitro ; Pancreatic islet cell carcinoma
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Tyr-3-Octreotide is a synthetic derivative of somatostatin and a somatostatin-receptor analogue. The iodine-123-labelled compound localizes somatostatin-receptor-positive tumours. In this paper two patients are reported in whom somatostatin receptors were demonstrated in vitro. In a 60-year-old female with an islet cell carcinoma of the pancreas, multiple liver metastases and previously unrecognized bone metastases in the right acetabulum could be diagnosed as the reason for a persistent hypoglycaemia. In a 60-year-old male an islet cell carcinoma of the pancreas was localized with123I-Tyr-3-octreotide. The somatostatin receptors were demonstrated in vitro and the tumour was successfully treated with somatostatin. These studies demonstrate that123I-Tyr-3-octreotide offers the possibility of localizing somatostatin-receptor-positive tumours and their metastases. Moreover the method makes it possible to determine the receptor status of a tumour in vivo.
    Type of Medium: Electronic Resource
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