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  • 1990-1994  (2)
  • (R)α-methylhistamine  (1)
  • Bacillus thuringiensis  (1)
  • [abr] BSA; bovine serum albumin
  • 1
    Electronic Resource
    Electronic Resource
    Springer
    Entomologia experimentalis et applicata 61 (1991), S. 179-187 
    ISSN: 1570-7458
    Keywords: Mechanism of resistance ; diamondback moth ; Plutellidae ; Bacillus thuringiensis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Abstract To determine whether field-selected resistance of diamondback moth (Plutella xylostella L.) (Lepidoptera: Plutellidae) to Bacillus thuringiensis is based on behavioral or physiological adaptation, we measured mortality, consumption, and movement of larvae from a susceptible and a resistant colony when placed on untreated and B. thuringiensis treated cabbage. Colonies did not differ in mortality, consumption, or movement on untreated cabbage. However, for a given amount of consumption of treated cabbage, resistant larvae had lower mortality than susceptible larvae, demonstrating that resistance had a physiological basis. The movement patterns could not account for the differences between colonies in survival. Resistant larvae did not avoid B. thuringiensis more than did susceptible larvae. Thus, we found no evidence for behavioral resistance.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Springer
    Naunyn-Schmiedeberg's archives of pharmacology 343 (1991), S. 225-227 
    ISSN: 1432-1912
    Keywords: Histamine H3 receptors ; Gastric acid secretion ; Conscious gastric fistula cat ; (R)α-methylhistamine ; Thioperamide
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary In an attempt to assess the role of histamine H3 receptors in the control of gastric acid secretion, the effects of the selective histamine H3 receptor agonist, (R)α-methylhistamine and antagonist, thioperamide were evaluated in the conscious gastric fistula cat under basal conditions and against different stimuli. (R)α-methylhistamine (0.05–0.2 μmol/kg/h) was ineffective against spontaneous and dimaprit-induced acid secretion; it also did not reduce significantly pentagastr-ininduced acid output, but caused a dose-dependent (0.05–0.1 μmol/kg/h) and significant inhibition of the acid response to 2-deoxy-d-glucose. Thioperamide (0.02–0.04 μmol/kg/h) did not modify spontaneous acid secretion, whereas it evoked a significant enhancement of the acid response to submaximal doses (50 mg/kg i. v.) of 2-deoxy-d-glucose. Thioperamide completely reversed the inhibitory effect of (R)α-methylhistamine against 2-deoxy-d-glucose-induced secretion, while leaving unaffected the inhibition induced by somatostatin. These data suggest that histamine H3 receptors may be involved in the control of acid secretion stimulated by indirectly acting secretagogues.
    Type of Medium: Electronic Resource
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