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  • 1
    ISSN: 1619-7089
    Keywords: Positron emission tomography ; 11C-amino acids ; 18F-fluorodeoxyglucose ; Prolactinoma ; Salivary gland
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Aspects of metabolism in prolactinomas were investigated by positron emission tomography using l-[1-11C]tyrosine, l-[methyl-11C]methionine and 18F-fluorodeoxyglucose (18FDG). Using l-[1-11C]tyrosine, four patients were monitored prior to and 18 h after an injection of 50 mg bromocryptine. At 18 h after bromocryptine intervention, l-[1-11C]tyrosine uptake into tumour was reduced with 28% (P〈0.07). A correlation analysis of the bromocryptine-induced decrease in l-[1-11C]tyrosine uptake and the reduction of serum prolactin levels indicated that the action of bromocryptine on prolactin synthesis and prolactin release is not coupled. In the untreated situation, the four patients were investigated with 18FDG as well, but the prolactinomas could not be visualized. Three untreated patients were studied with l-[methyl-11C]methionine. The tumour-imaging potential of l-[methyl-11C]methionine and l-[1-11C]tyrosine appeared to be nearly equivalent for prolactinomas. Unlike prolactinoma tissue, the salivary glands showed a pronounced preference for l-[1-11C]tyrosine as compared to l-[methyl-11C]methionine. l-[1-11C]tyrosine is a valuable tool to obtain information on the metabolism and treatment of prolactinomas.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 1573-1561
    Keywords: 1,4-Benzoxazin-3-ones ; hydroxamic acids ; 2,4-dihydroxy-7-methoxy-1,4-benzoxazin-3-one (DIMBOA) ; Coleoptera ; Chrysomelidae ; Diabrotica virgifera virgifera ; corn rootworms ; nonpreference ; search behavior ; chemical ecology
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract Hydroxamic acids have been shown to be toxic to many pest insects and pathogens. In this study, the behavioral responses of western corn rootworm larvae to naturally occurring and synthetic hydroxamic acids were investigated. In a choice test between corn roots treated with hydroxamic acids and roots treated with distilled water (control), western corn rootworm larvae chose to burrow into the control roots significantly more often than compoundtreated roots. In addition, when corn roots were treated with different hydroxamic acids in a designed searching-behavior test, neonate larvae of western corn rootworm responded by significantly reducing the number of turns, while the area searched and locomotor rate significantly increased. The responses were dependent on the concentrations of the test compounds. These results suggested that hydroxamic acids were acting as behavior-modifying and possibly feeding-deterrent chemicals.
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1572-9508
    Keywords: camera ; 10 micron ; Saturn
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract This paper presents the general features of the “C10μ” camera, now in routine operation at the CFHT, with initial results on CVF observations of the C2H2 and C2H6 bands and the continuum in the atmospher e of Saturn.
    Type of Medium: Electronic Resource
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