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  • 1
    Electronic Resource
    Electronic Resource
    Dexamethasone treatment fails to increase arginine-induced insulin release in healthy subjects with low insulin response (1992)
    Springer
    Diabetologia 35 (1992), S. 367-371 
    Details
    ISSN: 1432-0428
    Keywords: Insulin secretion ; Type 2 (non-insulin-dependent) diabetes mellitus ; glucagon secretion ; C-peptide ; arginine ; dexamethasone
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We have compared insulin responses to L-arginine before and during dexamethasone treatment in healthy subjects, previously classified as subjects with either high or low insulin response according to a standardized glucose infusion test. Arginine stimulation was administered as a 150 mg/kg bolus followed by 10 mg·kg−1·min−1 to six subjects with high insulin response and to seven subjects with low insulin response. Before dexamethasone treatment the incremental insulin level during 0–10 min of arginine was higher in subjects with high (36.5±6.8 μU/ml) than in subjects with low response (14.5±2.3 μU/ml), p〈0.01 for difference. Dexamethasone treatment (6 mg/day for 60 h) markedly enhanced the insulin response to arginine in subjects with high response (+99% 0–30 min) but failed to affect the subjects with low response (+4% 0–30 min). The C-peptide response to arginine exhibited similar differences between groups. Decreased responsiveness to arginine in subjects with low insulin response, especially during dexamethasone treatment, suggests a Beta-cell capacity defect although a decreased potentiating-sensing effect of glucose cannot be completely ruled out.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00401204
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  • 2
    Electronic Resource
    Electronic Resource
    Absolute partial and total electron impact ionization cross sections for C3H8 from threshold up to 950 eV (1993)
    Springer
    The European physical journal 25 (1993), S. 217-226 
    Details
    ISSN: 1434-6079
    Keywords: 34.80.Gs ; 35.20.Wg
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract Electron impact ionization of propane (C3H8) was studied using the ion beam deflection technique and a double focussing mass spectrometer in conjunction with a recently developed correction procedure that accounts for discrimination due to the initial kinetic energy of fragment ions. The relative corrected partial ionization cross sections for the production of C3H 8 + , C3H 7 + , C3H 6 + , C3H 5 + , C3H 4 + , C3H 3 + , C3H 2 + , C3H+, C 3 + ; C2H 5 + , C2H 4 + , C2H 3 + , C2H 2 + , C2H+, C 2 + ; CH 3 + , CH 2 + , CH+, C+; C3H 5 2+ , C3H 4 2+ , C3H 3 2+ and C3H 2 2+ were determined from threshold up to 950 eV. Absolute partial ionization cross sections were obtained by charge weighted summing of all the observed partial ionization cross sections and by normalizing to a recent accurate determination of the total ionization cross section at 100 eV by Djuric et al. 1991. The absolute total ionization cross section curve obtained is in excellent agreement in shape and magnitude with the low energy data (〈200 eV) of Djuric et al. 1991 and the high energy data points of Schram et al. 1966.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01426883
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    Paper (German National Licenses)
    Fulltext
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