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  • 1990-1994  (3)
  • Alkylphosphonium salts  (1)
  • Cell & Developmental Biology  (1)
  • Endometrium  (1)
  • 1
    Electronic Resource
    Electronic Resource
    The distribution and possible function of gamma interferon-immunoreactive cells in normal endometrium and myometrium (1992)
    Springer
    Virchows Archiv 420 (1992), S. 419-424 
    Details
    ISSN: 1432-2307
    Keywords: Endometrium ; Myometrium ; Lymphocytes ; Gamma interferon
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary T-lymphocytes are present in normal endometrium, where they may have a role in the control of glandular maturation. T-cell activity could be related to the local secretion of cytokines such as gamma interferon, which has an anti-proliferative effect on endometrial epithelial cells in vitro. We have examined gamma interferon immunoreactivity and T-cell distribution in 24 normal pre-menopausal uteri. Endometrial appearances were representative of all stages of the menstrual cycle. Most cells in the lymphoid aggregates in the stratum basalis were stained by T-cell and gamma interferon antisera. T-lymphocytes were also scattered in glandular epithelium and throughout the stroma of basal and functional layers; immunoreactivity for gamma interferon was less consistent in these cells. There was no alteration in the intensity or distribution of gamma interferon staining in different phases of the menstrual cycle. Endometrial granulocytes (K-cells) present mainly in the late secretory endometria were not reactive with the gamma interferon antiserum. In addition to endometrial staining, T-cells were distributed in all areas of the myometrium in most uteri, and many myometrial lymphocytes were gamma interferon positive. These results support a role for gamma interferon in endometrial physiology, possibly as an inhibitor of epithelial proliferation.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01600513
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Identification of a program of contractile protein gene expression initiated upon skeletal muscle differentiation (1993)
    New York, NY [u.a.] : Wiley-Blackwell
    Developmental Dynamics 196 (1993), S. 25-36 
    Details
    ISSN: 1058-8388
    Keywords: Contractile protein genes ; Skeletal muscle ; Regeneration ; Differentiation ; Rodent ; Human ; Genetic program ; Life and Medical Sciences ; Cell & Developmental Biology
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Medicine
    Notes: The functional diversity of skeletal muscle is largely determined by the combinations of contractile protein isoforms that are expressed in different fibers. Just how the developmental expression of this large array of genes is regulated to give functional phenotypes is thus of great interest. In the present study, we perform a comprehensive analysis of contractile protein isoform mRNA profiles in skeletal muscle systems representing each generation of fiber formed: primary, secondary, and regenerating fibers. We find that in each system examined there is a common pattern of isoform gene expression during early differentiation for 5 of the 6 gene families we have investigated: myosin light chain (MLC)1, MLC2, tropomyosin, troponin (Tn)C, and TnI. We suggest that the common isoform patterns observed together represent a genetic program of skeletal muscle differentiation that is independent of the mature fiber phenotype and is found in all newly formed myotubes. Within each of these contractile protein gene families the program is independent of the isoforms of myosin heavy chain (MHC) expressed. The maintenance of such a program may reflect a specific requirement of the initial differentiation process. © 1993 wiley-Liss, Inc.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/aja.1001960104
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    Paper (German National Licenses)
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  • 3
    Electronic Resource
    Electronic Resource
    Carbon-13 and related NMR chemical shifts in alkylammonium and alkylphosphonium salts (1990)
    Chichester : Wiley-Blackwell
    Organic Magnetic Resonance 28 (1990), S. 711-714 
    Details
    ISSN: 0749-1581
    Keywords: Alkylammonium salts ; Alkylphosphonium salts ; Iron-sulphur cluster ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The 13C NMR chemical shifts of the α-carbon atoms in cations [NR4]+, [NR3CH2Ph]+ and [PR4]+ [R = Me, Et, Prn, Bun or Pen (n-pentyl)] are found at anomalously high field in comparison with the corresponding shifts in RCl or RNH2. This is ascribed in part to the effect of the positive charge. The effect is detectable but less pronounced with β-carbon atoms, but is not detectable in subsequent carbon atoms in longer alkyl chains.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/mrc.1260280810
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    Paper (German National Licenses)
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