Library

X
feed icon rss

Your email was sent successfully. Check your inbox.

An error occurred while sending the email. Please try again.

Proceed reservation?

Export
Filter
  • 1990-1994  (2)
  • Aortic valve  (1)
  • Deletion  (1)
  • 1
    Electronic Resource
    Electronic Resource
    A specific 4977-bp deletion of mitochondrial DNA in human ageing skin (1994)
    Springer
    Archives of dermatological research 286 (1994), S. 386-390 
    Details
    ISSN: 1432-069X
    Keywords: Skin ageing ; Mitochondrial DNA ; Deletion
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Mitochondrial DNA (mtDNA) mutations have recently been proposed as important contributors to ageing and degenerative diseases. In this study, we applied the polymerase chain reaction technique to detect 4.977 bp-deleted mtDNA, the most common and abundant deletion of mtDNA, in normal human skin. None of the skin specimens from patients less than 60 years of age were found to bear this type of mtDNA deletion. The incidence of the 4977-bp-deleted mtDNA increased with advancing age. The incidence of the deletion was 20%, 46.7% and 83.4% for patients of the age groups of 61–70, 71–80, and 81–90 years, respectively. Moreover, the incidence of 4977-bp-deleted mtDNA was significantly higher in exposed skin than that in non-exposed skin. We suggest that mtDNA mutations are molecular events associated with the human skin ageing process.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00371798
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Cardiac doppler blood-flow signal analysis (1993)
    Springer
    Medical & biological engineering & computing 31 (1993), S. 237-241 
    Details
    ISSN: 1741-0444
    Keywords: Aortic valve ; Doppler ultrasound ; Normality test ; Signal processing ; Stationarity test
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology , Medicine
    Notes: Abstract The normality (Gaussian property) and stationarity of the cardiac Doppler blood-flow signal were evaluated on short-time segments distributed over the cardiac cycle. The basic approaches used to perform statistical tests on the nonstationary and quasiperiodic cardiac Doppler signal are presented. The results obtained from the data of ten patients having a normal aortic valve and ten patients having a stenotic valve indicate that a complex Gaussian random process is an acceptable approximation for the clinical cardiac Doppler signal. For segments of 10 ms or less, 82 per cent of them were accepted to be stationary with a significance level of 0.05, whereas for durations greater than 40 ms, the percentage of stationary segments was less than 75 per cent. It was concluded that the 10ms window generally used in practice is a good choice for Doppler spectrogram estimation, but a shorter time interval would be preferable.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02458042
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
Close ⊗
This website uses cookies and the analysis tool Matomo. More information can be found here...