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  • 1990-1994  (2)
  • Candida albicans  (1)
  • cataract  (1)
  • 1
    Electronic Resource
    Electronic Resource
    A novel antifungal from an Actinomadurae with preferential activity against the mycelial phase ofCandida albicans (1991)
    Springer
    Journal of industrial microbiology and biotechnology 8 (1991), S. 65-68 
    Details
    ISSN: 1476-5535
    Keywords: Antifungal ; Sch 40873 ; Candida albicans ; Mycelial
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Process Engineering, Biotechnology, Nutrition Technology
    Notes: Summary Sch 40873, a novel antifungal compound isolated from the fermentation broth of anActinomadura spp. was discovered in an assay designed to detect compounds with preferential activity against the invasive mycelial form ofCandida albicans. The geometric mean MIC of Sch 40873 against sevenCandida spp. in Sabouraud dextrose broth (yeast phase) was ≥58 μg/ml and in Eagles minimum essential medium (mycelial phase) was 〈0.03 μg/ml. Sch 40873 demonstrated slight in vivo topical activity in a hamster vaginal model.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01575593
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
  • 2
    Electronic Resource
    Electronic Resource
    Antilens antibodies in cataract and inflammatory eye disease: an evaluation of a new technique (1990)
    Springer
    International ophthalmology 14 (1990), S. 97-100 
    Details
    ISSN: 1573-2630
    Keywords: antilens antibodies ; immunoassay ; cataract ; uveitis
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A new technique measuring serum antoantibodies to lens proteins, employing antigen linked to magnetisable cellulose particles and fluorescent end-point detection, was used to examine patients with senile cataract and inflammatory eye disease. 40% of patients with senile cataract had antibodies to lens proteins, as did 28% of patients with heterochromic cyclitis and 20% of patients with uveitis, while there were no positive sera from patients with scleritis. The single patient with lens-induced uveitis had a high titre, but so did some patients with senile cataract. With the incorporation of a standard curve this technique offers a reliable quantitative assay for lens autoantibodies. It may provide a valuable tool for the investigation of pathogenet ic mechanisms in cataract and inflammatory eye disease.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00154208
    Library Location Call Number Volume/Issue/Year Availability
    BibTip Others were also interested in ...
    Paper (German National Licenses)
    Fulltext
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