ISSN:
0951-4198
Keywords:
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Physics
Notes:
A new ion desorption method is described that utilizes a primary beam of massive, multiply charged cluster ions to generate secondary ions of peptides in a glycerol matrix. The massive cluster ion beam is generated via electrohydrodynamic emission using a 1.5 M solution of ammonium acetate in 30% aqueous glycerol. Negaitve ion spectra of peptides obtained using this technique show greatly decreased relative intensities for fragment ions and ‘chemical noise’ background when compared to spectra obtained using a xenon atom primary beam. The near absence of fragmets derived from radiation damage to the sample solution is attributed to the impact of primary particles with energies less than 1 eV/nucleon.
Additional Material:
3 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/rcm.1290051004
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