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  • 1
    ISSN: 1432-1971
    Keywords: Age ; Heart rate variability ; Spectral analysis ; Cholinergic ; Adrenergic
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary We compared heart rate variability measures of 11 normal children (4–12 years) to 23 normal adults (21–43 years) to study the effect of age on heart rate variability measures. Children had a significantly higher supine and standing heart rate and lower supine and standing systolic diastolic blood pressure. Children also had a significantly higher supine standard deviation of HR, supine low frequency (0.01–0.05 Hz) (p〈0.005), supine high frequency (0.2–0.5 Hz) (p〈0.001), and standing high frequency powers (p〈0.005) compared to adults. The ratio of mid frequency (0.07–0.15 Hz) to high frequency power (0.2–0.5 Hz) upon standing was significantly lower in children (p〈0.005). While there was a significant increase of the mid frequency power from supine to standing posture in the adult group (p〈0.02), there was no such significant increase in children. There were also significant negative correlations between age and supine low frequency, mid frequency, and high frequency powers, and standing high frequency power. These findings illustrate a decrease of cholinergic and an increase of adrenergic modulation of heart rate variability with age (4–43 years).
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Berlin : Wiley-Blackwell
    Acta Biotechnologica 10 (1990), S. 55-61 
    ISSN: 0138-4988
    Keywords: Life Sciences ; Life Sciences (general)
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Notes: High-molecular weight pectic acid with a STAUDINGER index of 210 ml/g and a degree of esterification of 3%was used as matrix material for the immobilization of Saccharomyces cerevisiae cells. In discontinuous and continuous fermentation tests the gel beads obtained exhibited the same biomass loading capacity (152-155 g dry wt. cells/kg gel) and about the same maximum specific productivity (103.0 g ethanol/kg gel · h) as alginate immobilizates. But there were distinct differences in the swelling behaviour of the two gels. Under the same experimental conditions the increase of bead volume amounted to 27% only for pectate gel in comparison to 129% for alginate gel. In continuous fermentation experiments performed in a horizontal-column packed-bed reactor with liquid recycling a mean steady-state ethanol concetration of 69.1 g/l and a mean productivity of 24.7 g ethanol/lh could be kept constant over a period of more than 10 days.
    Additional Material: 2 Ill.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Berlin : Wiley-Blackwell
    Acta Biotechnologica 10 (1990), S. 523-529 
    ISSN: 0138-4988
    Keywords: Life Sciences ; Life Sciences (general)
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Notes: The production of cellulase was investigated in repeated batch experiments using immobilized cells of two Trichoderma reesei mutants in a rotating disc fermenter under very low shear stress. The enzyme production with one of the mutants was maintained for three successive batch cycles (ca. 30 days), while with the other mutant the cellulase formation lasted only one batch cycle (14 days) because of a genetic instability.The enzymatic hydrolysis of microcrystalline cellulose by the cellulase complex formed in the rotating disc fermenter is distinctly higher than that of cellulase produced in a stirred tank reactor, in which the higher shear stress partially damages the enzyme molecules, mainly those of cellobiohydrolase. The higher specific activity of the cellulase produced in the disc fermenter correlates with its higher capacity of adsorption onto microcrystalline cellulose.
    Additional Material: 5 Ill.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 0138-4988
    Keywords: Life Sciences ; Life Sciences (general)
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Process Engineering, Biotechnology, Nutrition Technology
    Notes: High-loaded pectate gels containing more than 1014 cells/l of gel (viability 〉 60%) were obtained. Immobbilizates of Lactobacillus sp. IMET 11466 showed a maximum mean gel activity of 120 g of lactate/l of gel * h. With the strain Streptococcus thermophilus Č 129 a value of 139 g of lactate/l of gel * h was attained. Using these immobilizates the conversion of 100 g of glucose/l with a yield of 90-95% can be realized in only 6-8 h. On the basis of a detailed analysis of the time course of the lactate-forming activity of the immobilizates during batch fermentations evidence is given of an analogy in the lactate-inhibitory behaviour of immobilized and free cells.
    Additional Material: 12 Ill.
    Type of Medium: Electronic Resource
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