ISSN:
0935-6304
Keywords:
Capillary GC
;
Enantiomer separation
;
Derivatized cyclodextrins
;
Chemistry
;
Analytical Chemistry and Spectroscopy
Source:
Wiley InterScience Backfile Collection 1832-2000
Topics:
Chemistry and Pharmacology
Notes:
This paper describes an evaluation of the chromatographic performance of columns coated with amorphous cyclodextrin (CD) derivatives, in particular 2,3,6-tripentyl-β-CD (2,3,6-TriPe-β-CD), 2,6-dipentyl-3-methyl-β-CD (2,6-DiPe-3-Me-β-CD), and 2,6-dimethyl-3-pentyl-β-CD (2,6-DiMe-3-Pe-β-CD), all diluted in polysiloxane (OV-1701 or OV-1701-OH), for the separation of the enantiomers of volatile compounds. 2,6-DiMe-3-Pe-β-CD in OV-1701 offers performance comparable with (or better than) that of the other two CDs, and without their drawbacks (inconsistency of results, as described previously).This article compares the separating ability of 2,6-DiMe-3-Pe-β-CD and 2,3,6-TriMe-β-CD, and describes the influence of the CD derivative to polysiloxane ratio, the minimum operating temperatures of the columns, and the reproducibility and consistency of performance of columns coated with the former CD derivative diluted in polysiloxane.
Additional Material:
5 Ill.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1002/jhrc.1240151104
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