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Digitale Medien

A strongly basic protein of the MAP2 family copolymerizes with tubulin and induces polymerization (1991)

Nguyen, Mai ; Fasold, Hugo

Springer

The protein journal 10 (1991), S. 511-516

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Details

ISSN: 1573-4943

Schlagwort(e): Microtubule-associated proteins ; MAP2 ; basic MAP

Quelle: Springer Online Journal Archives 1860-2000

Thema: Chemie und Pharmazie

Notizen: Abstract The family of microtubuli-associated proteins of approximately 300 kD molecular weight (MAP2) from porcine brain was fractionated into components of neutral isoelectric point and one polypeptide of strongly basic nature. Both fractions are able to induce the polymerization of purified porcine brain tubulin. In the case of the fractions of an isoelectric point of 7.2, thick and short tubular structures result. Under the influence of the basic protein, extremely long tubules of normal diameter of microtubules are produced. This basic MAP2 copolymerizes with tubulin.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF01025479

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