ISSN:
1432-2307
Keywords:
Nodular regenerative hyperplasia of the liver
;
Liver metastasis
;
Pancreatic endocrine tumour
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Summary Two autopsy cases with multiple hepatic metastases of pancreatic endocrine tumours and nodular regenerative hyperplasia of the liver (NRH) are reported. The tumour cells were positive for glucagon, insulin, gastrin and vasoactive intestinal polypeptide immunohistochemically and the serum gastrin was elevated in one case. In the other, tumour cells were positive for insulin. Controls failed to show NRH in the non-metastatic part of 35 autopsies of livers with multiple hepatic metastases. A combination of hepatotrophic hormonal factor(s) and disturbed hepatic circulation associated with hepatic metastases may be important in the development of NRH.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF01607051
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