ISSN:
1432-0983
Keywords:
Saccharomyces cerevisiae
;
Nucleo-mitochondrial interactions
;
Mitochondrial status
;
Lycorine
Source:
Springer Online Journal Archives 1860-2000
Topics:
Biology
Notes:
Summary In a previous paper we have shown that the alkaloid lycorine inhibits growth of rho +, mit - and rho -, strains of Saccharomyces cerevisiae, whereas strains devoid of mitochondrial DNA (rho o) are resistant to more than 200 μg/ml of the alkaloid. In this report we show that hypersuppressive petites are almost as resistant as rho o mutants, whereas isogenic rho - petites, which have retained tained longer segments of the genome, are sensitive to the drug.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00334527
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