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Digitale Medien

Genetic control of polyketide biosynthesis in the genusStreptomyces (1993)

Hutchinson, C. Richard ; Decker, Heinrich ; Madduri, Krishnamurthy ; [weitere]

Springer

Antonie van Leeuwenhoek 64 (1993), S. 165-176

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Details

ISSN: 1572-9699

Schlagwort(e): actinorhodin ; antibiotics ; daunorubicin ; erythromycin ; tetracenomycin ; tylosin

Quelle: Springer Online Journal Archives 1860-2000

Thema: Biologie

Notizen: Abstract The genetic control of polyketide metabolite biosynthesis inStreptomyces sp. producing actinorhodin, daunorubicin, erythromycin, spiramycin, tetracenomycin and tylosin is reviewed. Several examples of positively-acting transcriptional regulators of polyketide metabolism are known, including some two-component sensor kinase-response regulator systems. Translational and posttranslational control mechanisms are only briefly mentioned since very little is known about either of these processes. Examples of how enzyme levels and substrate supply affect polyketide metabolism also are discussed.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00873025

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