Bibliothek

feed icon rss

Ihre E-Mail wurde erfolgreich gesendet. Bitte prüfen Sie Ihren Maileingang.

Leider ist ein Fehler beim E-Mail-Versand aufgetreten. Bitte versuchen Sie es erneut.

Vorgang fortführen?

Exportieren
  • 1
    ISSN: 1573-4919
    Schlagwort(e): Zucker rat ; amino acid metabolism ; skeletal muscle ; obesity
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Chemie und Pharmazie , Medizin
    Notizen: Abstract Measurements of the tissue accumulation of α-amino[1-14C]isobutyrate [1-14C]AIB) in lean (+/?) and obese (fa/fa) Zucker rats showed an augmented tissue/plasma ratio in the liver of the obese animals. In contrast, brown adipose tissue AIB accumulation was lower in the fa/fa animals. In response to a 24h starvation period AIB accumulation was significantly elevated in the liver and plasma of the lean animals and was unchanged in the liver of the fa/fa animals. The circulating concentration of alanine and branched-chain amino acids was elevated in the fa/fa animals as compared to their lean counterparts. These observations suggest that amino acid uptake is not involved in the impaired muscle development observed in the obese Zucker rat and that the ability of brown adipose tissue for amino acid utilization is decreased in the obese animals suggesting that this may partially explain the impaired thermoregulatory capacity observed in brown adipose tissue of obese Zucker rats.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 2
    Digitale Medien
    Digitale Medien
    Springer
    Molecular and cellular biochemistry 125 (1993), S. 11-18 
    ISSN: 1573-4919
    Schlagwort(e): tumor necrosis factor ; cytokines ; protein metabolism ; skeletal muscle
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Chemie und Pharmazie , Medizin
    Notizen: Abstract Acute treatment of rats with recombinant tumour necrosis factor (TNF-α) caused an enhanced proteolytic rate —measured as tyrosine released in the presence of cycloheximide — insoleus muscle (34%). The cytokine treatment also decreased the rate of protein synthesis in this muscle (22%) while it had no effect upon the same parameter inextensor digitorum longus (EDL) (26%) muscle. In addition, treatment of rats with TNF-α increased amino acid uptake by transport system A in the incubated muscles both insoleus (45%) andEDL (99%) in the presence of insulin in the incubating medium. This effect was not associated with a direct action of TNF on muscle since the addition of different concentrations of the cytokine to the preparations did not alter the uptake of α-(methyl)-aminoisobutyric acid by the incubated muscles. It can be concluded that acute TNF-α treatment causes changes in protein metabolism in red-type muscles — suchsoleus — while little effects are seen in white-type muscles — such as EDL. The results presented may, to some extent, be related to the cachectic response associated with cancer and inflammation.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 3
    ISSN: 1573-5060
    Schlagwort(e): common bean ; Phaseolus vulgaris ; bean golden mosaic virus ; selection ; interracial population ; recombinant inbreds
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Land- und Forstwirtschaft, Gartenbau, Fischereiwirtschaft, Hauswirtschaft
    Notizen: Summary Eighty-three F2-derived F8 recombinant inbred lines (RILs) randomly selected from a population (TY 8419) of two common bean genotypes (Pinto UI 114 x ICA Pijao), the two parents, and a control cultivar (Topcrop) were screened for their reaction to bean golden mosaic virus (BGMV) under glasshouse conditions. A randomized complete block design with two replications was used. Data were recorded for disease incidence, foliar yellowing, number of pods and seeds, and yield. Significant (P〈0.05) differences among the 83 RILs were recorded for all traits. Of these RILs, 11 lines did not develop any symptom, 24 lines had a mean disease incidence of 8%, 28 lines had a disease incidence of 26.6% and developed intermediate mosaic symptoms, and 20 lines were more susceptible (〉50% disease incidence and severe yellowing) than either of the parents, which had 25% to 38% disease incidence and moderate symptoms. Heritability for disease incidence was 0.54±0.01, for foliar yellowing 0.36±0.13, for pods plant-1 0.69±0.01, for seeds plant-1 0.54±0.09, and for yield plant-1 0.49±0.01. Gains from selection (at 20% selection pressure) for these traits were 49.5%, 31.6%, 24%, 0%, and 20%, respectively, over the mean value of all RILs. Correlation coefficients between disease incidence and foliar yellowing and among yield and its components were positive. Disease incidence and foliar yellowing showed negative associations with yield and its components.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 4
    Digitale Medien
    Digitale Medien
    Springer
    Euphytica 52 (1991), S. 113-117 
    ISSN: 1573-5060
    Schlagwort(e): Phaseolus vulgaris ; common bean ; bean golden mosaic virus ; resistance sources ; general combining ability ; genetics ; breeding
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Land- und Forstwirtschaft, Gartenbau, Fischereiwirtschaft, Hauswirtschaft
    Notizen: Summary The genetics of resistance to bean golden mosaic virus (BGMV) was studied in an 8×8 complete diallel cross of common bean, Phaseolus vulgaris L. The 28F1 hybrids, their reciprocals, and eight parents were artificially inoculated with BGMV under glasshouse conditions. Data were recorded and analyzed for foliar yellowing, plant dwarfing, flower abortion, and pod formation, using a randomized complete block design with two replications. General combining ability (GCA) mean squares were highly significant (P〈0.01) and larger than values for specific combining ability for all traits. Reciprocal and maternal effects were nonsignificant. Cultivars Royal Red and Alubia Cerrillos possessed significant negative and positive GCA for all traits, respectively. Porrillo Sintetico also had negative GCA for all traits except plant dwarfing. None of the GCA effects were significant for Great Northern 31 and PVA 1111. Positive associations existed among all traits studied.
    Materialart: Digitale Medien
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
Schließen ⊗
Diese Webseite nutzt Cookies und das Analyse-Tool Matomo. Weitere Informationen finden Sie hier...