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  • 11
    Electronic Resource
    Electronic Resource
    Influence of Pb doping on properties of BSCCO superconductor (1991)
    Springer
    Il nuovo cimento della Società Italiana di Fisica 13 (1991), S. 1315-1319 
    Details
    ISSN: 0392-6737
    Keywords: Superconducting materials
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Summary We report here about measurements of resistancevs. temperature, alternating current (a.c.) susceptibility and X-ray diffraction performed on Ba2Sr2Ca2Cu3O x superconductor doped with various amounts of Pb. The results could be explained in terms of Pb contribution in increasing both the amount of the highestT C 0 phase and connectivity between superconductive regions. The Pb substitution on Bi sites is also discussed.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02458738
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  • 12
    Electronic Resource
    Electronic Resource
    Coordination mode of 4-pyridinecarbaldehyde phenylhydrazone. Structure of dichloro(4-pyridinecarbaldehyde phenylhydrazone)(tri-n-propylphosphine)palladium(II) (1990)
    Oxford [u.a.] : International Union of Crystallography (IUCr)
    Acta crystallographica 46 (1990), S. 192-195 
    Details
    ISSN: 1600-5759
    Source: Crystallography Journals Online : IUCR Backfile Archive 1948-2001
    Topics: Chemistry and Pharmacology , Geosciences , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1107/S0108270189005731
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  • 13
    Electronic Resource
    Electronic Resource
    A population-based prevalence survey of known diabetes mellitus in Northern Italy based upon multiple independent sources of ascertainment (1992)
    Springer
    Diabetologia 35 (1992), S. 851-856 
    Details
    ISSN: 1432-0428
    Keywords: Epidemiology ; prevalence of diabetes mellitus ; population survey ; Italy
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary The aims of this survey were (1) to estimate the prevalence of known diabetes mellitus in 1988 in Casale Monferrato (Northern Italy); (2) to validate different data sources available in Italy; (3) to identify a population-based cohort of diabetic patients. Multiple independent data sources were used and the capture-recapture method was applied to estimate the completeness of ascertainment of the survey. The primary data source was the list of all patients attending the diabetic clinic or those referred by family physicians and paediatricians of the area. The secondary data sources were the list of hospital discharges, the prescriptions data source and the list of all people using reagent strips and insulin syringes. On 1 October 1988 (the cut-off date) 2,069 cases of known diabetes were identified. The estimated completeness of ascertainment of the survey was 91%. Prevalence of known diabetes, Type 1 (insulin-dependent), Type 2 (non-insulin-dependent) and insulin-treated diabetes were, respectively, 2.21% (95% CI 2.13–2.29), 0.80/1,000 (0.62–0.98) and 2.10% (2.01–2.19), 2.92/1,000 (2.57–3.27). A higher prevalence of Type 2 diabetes was observed in women (2.30%, 2.18–2.42) than in men (1.88%, 1.76–2.00). Age-specific prevalence of Type 2 diabetes increased with age. Computerized data sources routinely available in the Piedmont Region (hospital discharges and prescriptions data sources) showed a low completeness of ascertainment when considered together (65%, 1,338 of 2,069), indicating the need to involve the diabetic clinic and family physicians in the ascertainment of known diabetes. In conclusion, the prevalence of known diabetes in Italy was lower than in Northern Europe and the United States.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00399931
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  • 14
    Electronic Resource
    Electronic Resource
    Allergenicity of milk protein hydrolysate formulae in children with cow's milk allergy (1993)
    Springer
    European journal of pediatrics 152 (1993), S. 760-762 
    Details
    ISSN: 1432-1076
    Keywords: Allergenicity ; Cow's milk allergy ; Cow's milk protein hydrolysate formulae
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Cow's milk protein hydrolysate formulae have been developed to lower or eliminate the allergenicity of cow's milk proteins, and to reduce the antigenic load and the risk of sensitization. Cross-reactivity between different hydrolysate formulae and cow's milk proteins has been demonstrated. We have studied 20 children (median age 31 months, range 15–76 months) with a history of IgE-mediated cow's milk allergy. All the children had immediate allergic respiratory and/or cutaneous and/or gastro-intestinal reactions to cow's milk ingestion. In addition, the children had positive prick skin tests and positive RAST to cow's milk. Prick skin test, RAST, and double-blind placebo controlled food challenges were performed with three different hydrolysate formulae: a casein hydrolysate formula and two whey formulae, one partially and one extensively hydrolyzed. All 20 children had immediate allergic reactions after the challenge test with cow's milk. Only 2/20 children had a positive challenge test with a casein hydrolysate formula (Alimentum): one developed asthma and one urticaria. Two of the 15 children challenged with an extensively hydrolysed whey formula (Profylac) developed perioral erythema. Nine out of 20 children had a positive challenge test with a partially hydrolysed whey formula (Nidina H.A.): four developed asthma, three urticaria and two lip oedema. All children had positive prick skin tests to cow's milk proteins (casein and/or lactalbumin); 9 to Nidina H.A.; 3 to Profylac, and 3 to Alimentum. Specific IgE antibodies to cow's milk were present in all children; in 13 to Nidina H.A., in 4 to Profylac, and in 3 to Alimentum.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01953996
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  • 15
    Electronic Resource
    Electronic Resource
    Adverse reaction to measles immunization (1993)
    Springer
    European journal of pediatrics 152 (1993), S. 80-80 
    Details
    ISSN: 1432-1076
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF02072524
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  • 16
    Electronic Resource
    Electronic Resource
    Saturable rate of cefatrizine absorption after oral administration to humans (1990)
    Springer
    Journal of pharmacokinetics and pharmacodynamics 18 (1990), S. 17-34 
    Details
    ISSN: 1573-8744
    Keywords: cefatrizine ; Michaelis-Menten equation ; saturable absorption rate
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract This study examined the absorption kinetics of cefatrizine, an amino-β-lactam antibiotic, after oral administration of a single 500-mg dose to 12 healthy volunteers. Plasma concentrations were determined by high performance liquid chromatography. The plots of the percentage of drug unabsorbed and the apparent rate of cefatrizine absorption as a function of time showed, first, a delay and, then, an almost constant rate of absorption with a tendency to move toward first-order kinetics at the end of the process. Three compartmental models incorporating a lag time and first-order elimination kinetics, but differing in their input rate, were used for analysis of the time course of cefatrizine plasma concentrations. The model with first-order absorption kinetics was clearly inadequate. The results were improved with the model for which the rate of absorption is constant, but a model incorporating saturable absorption kinetics of the Michaelis-Menten type improved the fit further. This last model was statistically superior to the constant-rate input model in 6 out of 12 subjects, according to the likelihood-ratio method. Because of the innovative feature of the model incorporating the Michaelis-Menten equation, simulations of the effect of altering the model parameters and the dose administered on the concentration-time profile, were performed. Different hypotheses which might explain why cefatrizine absorption kinetics fits the Michaelis-Menten equation were examined. The observation of saturable absorption kinetics is consistent with a carrier-mediated transport previously reported to occur in the gastrointestinal tract of rats.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01063620
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  • 17
    Electronic Resource
    Electronic Resource
    Introducing a new cannula: a versatile cannula for use with the machine and with the syringe (1993)
    Springer
    European journal of plastic surgery 16 (1993), S. 107-108 
    Details
    ISSN: 1435-0130
    Keywords: Lipoplasty ; New cannula
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A new liposuction cannula which can be used both with the syringe and with the machine has been produced by the author.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00196443
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  • 18
    Electronic Resource
    Electronic Resource
    Disposition, Bioavailability, and Serum Protein Binding of Pentachlorophenol in the B6C3F1 Mouse (1992)
    Springer
    Pharmaceutical research 9 (1992), S. 1053-1057 
    Details
    ISSN: 1573-904X
    Keywords: pentachlorophenol ; tetrachlorohydroquinone ; toxicokinetics ; metabolism
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract The toxicokinetics of pentachlorophenol (PCP) were studied in B6C3F1 mice, a strain in which PCP was previously found to be carcinogenic. In a crossover design, doses of 15 mg/kg were given intravenously (bolus) and orally (gastric intubation) to six animals. Concentrations of PCP in blood, urine, and feces were measured by capillary gas chromatography with electron-capture detection. After intravenous administration, the values of clearance and volume of distribution were 0.057 ± 0.007 L/hr/kg and 0.43 ± 0.06 L/kg, respectively. These two parameters exhibited low intermouse variability (coefficients of variation 〈14%). The elimination half-life was 5.2 ± 0.6 hr. After oral administration, the PCP peak plasma concentration (28 ± 7 µg/ml) occurred at 1.5 ± 0.5 hr and absorption was complete (bioavailability = 1.06 ± 0.09). The elimination half-life was 5.8 ± 0.6 hr. Only 8% of the PCP dose was excreted unchanged by the kidney. PCP was primarily recovered in urine as conjugates. A portion of the dose was recovered in urine as the mutagen, tetrachlorohydroquinone (5%) (TCHQ), and its conjugates (15%). For both PCP and TCHQ, sulfates accounted for 90% or more of the total conjugates (glucuronides and sulfates).
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1023/A:1015810629245
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  • 19
    Electronic Resource
    Electronic Resource
    Isotope effects on 31P nuclear shielding in thiophosphites (1991)
    Chichester : Wiley-Blackwell
    Organic Magnetic Resonance 29 (1991), S. 231-237 
    Details
    ISSN: 0749-1581
    Keywords: 31P NMR isotope effects ; Phosphorotrithioous acid, triesters ; Phosphorotrithioic acid, S,S,S-triesters ; Tetraphosphorus trisulphide ; Tetraphosphorus heptasulphide ; Tetraphosphorus octasulphide ; Tetraphosphorus nonasulphide ; Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: The 34S isotope effect on the chemical shift of PIII nuclei in P(SR)3 esters [R = Et, (C12H25)n, Ph] is close to 20.6 ppb per PIII—34S bond, i.e. 3-4 times larger than for thiolo sulphur atoms in S = P(SR)3 or O = P(SR)3. A similar behaviour is noted for the P(—S—)3 sites in P4S9 and P4S3 and for the downfield triplet of P4S8, which, accordingly, is assigned to the tri-coordinate P atoms of this sulphide. 13C isotope effects are also reported for trialkyl(aryl) phosphorotrithioites and S,S,S-phosphorotrithioates.
    Additional Material: 3 Ill.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1002/mrc.1260290307
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