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  • 1990-1994  (3)
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  • 1990-1994  (3)
Year
  • 1
    Electronic Resource
    Electronic Resource
    In vitro sodium salicylate release from chitosan films (1993)
    Springer
    Polymer bulletin 31 (1993), S. 375-379 
    Details
    ISSN: 1436-2449
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Summary In order to evaluate the applicability of chitosan membranes in controlled release systems, a reservoir-type device was designed. Sodium salicylate was chosen as model drug. The rate of release was measured in water at 37°±0.5° C and the amount of drug released was determined by spectrophotometric analysis. The results showed that sodium salicylate release followed a zero order kinetics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00692966
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
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  • 2
    Electronic Resource
    Electronic Resource
    Sulfonamide release from cellulose acetate membranes (1991)
    Springer
    Polymer bulletin 26 (1991), S. 529-534 
    Details
    ISSN: 1436-2449
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Summary Cellulose acetate membranes were chemically modified by esterification with oxalyl chloride which was used as a hydrolytically labile spacer. Then five sulfonamides were attached to the acyl chloride present on the halfesterified membranes to give drug-polymer conjugates. The rate of the hydrolytic cleavage of the spacer-drug linkage was measured in simulated gastric fluids at 37°±0.5°C by determining the amount of drug released by spectrophotometric analysis. The results showed that in all cases the process followed a zero-order kinetics.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF01032678
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    Paper (German National Licenses)
    Fulltext
  • 3
    Electronic Resource
    Electronic Resource
    In vitro drug release from chitosan membranes (1994)
    Springer
    Polymer bulletin 32 (1994), S. 69-75 
    Details
    ISSN: 1436-2449
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology , Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Summary In vitro studies of controlled release from chitosan membranes were carried out using drugs of different molecular weight. The release rate was measured in water at 37°±0.5°C by determining the amount of drug released by spectrophotometric analysis. It was found that release of acetamide, nicotinamide, sodium benzoate, sodium salicylate, phenobarbital sodium and sodium cefazoline followed zero-order kinetics. The relation between molecular weight and diffusion coefficient was established.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1007/BF00297416
    Library Location Call Number Volume/Issue/Year Availability
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    Paper (German National Licenses)
    Fulltext
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